The use of D. purpurea extract containing cardiac glycosides for the treatment of heart conditions was first described in the English-speaking medical literature by William Withering, in 1785, which is considered the beginning of modern therapeutics. It is used to increase cardiac contractility ( it is a positive inotrope ) and as an antiarrhythmic agent to control the heart rate, particularly in the irregular ( and often fast ) atrial fibrillation.

Despite this uncertainty, fourteen individuals have been identified as having verifiably attended Lunar Society meetings regularly over a long period during its most productive eras: these are Matthew Boulton, Erasmus Darwin, Thomas Day, Richard Lovell Edgeworth, Samuel Galton, Jr., James Keir, Joseph Priestley, William Small, Jonathan Stokes, James Watt, Josiah Wedgwood, John Whitehurst and William Withering.

William Withering – like Small a physician – was already an acquaintance of Darwin, Boulton and Wedgwood when he moved from Stafford to Birmingham and became a member of the Society in 1776.

The botanist and physician Jonathan Stokes, who had known William Withering as a child, moved to Stourbridge and started attending Lunar Society meetings from 1783.

Clinical pharmacology owes much of its foundation to the work of William Withering.

William Withering ( 17 March 1741 – 6 October 1799 ) was an English botanist, geologist, chemist, physician and the discoverer of digitalis.

Withering wrote two more editions of this work in 1787 and 1792, in collaboration with fellow Lunar Society member Jonathan Stokes, and after his death his son ( also William ) published four more.

The William Withering Chair in Medicine at the University of Birmingham Medical School is named after him, as is the medical school's annual William Withering Lecture.

William Withering analysing thermal waters in Portugal He was an enthusiastic chemist and geologist.

* William Withering Junior ( 1822 ).

William Withering of Birmingham.

William Withering and the Foxglove.

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* 1785 – William Withering publishes " An Account of the Foxglove " the first systematic description of digitalis in treating dropsy

* William Withering publishes An Account of the Foxglove and some of its Medical Uses.

1785: William Withering publishes An Account of the Foxglove and some of its Medical Uses, pioneering its use as a cardiac drug, Digitalis.

William Styron, while facing the changing economy with a certain uneasy reluctance, insists he is not to be classified as a Southern writer and yet includes traditional Southern concepts in everything he publishes.

he collaborated on a song with William Hartman Woodin, who was Secretary of the Treasury, 1932-33.

William Wimsatt and Cleanth Brooks, it seems to me, have a penetrating insight into the way in which this control is effected: `` For if we say poetry is to talk of beauty and love ( and yet not aim at exciting erotic emotion or even an emotion of Platonic esteem ) and if it is to talk of anger and murder ( and yet not aim at arousing anger and indignation ) -- then it may be that the poetic way of dealing with these emotions will not be any kind of intensification, compounding, or magnification, or any direct assault upon the affections at all.

In much the same way, we recognize the importance of Shakespeare's familarity with Plutarch and Montaigne, of Shelley's study of Plato's dialogues, and of Coleridge's enthusiastic plundering of the writings of many philosophers and theologians from Plato to Schelling and William Godwin, through which so many abstract ideas were brought to the attention of English men of letters.

William Coddington, who was running the colony, felt constrained to move seven miles south where, with others -- as mentioned above -- he founded Newport.

The Scots had found a new leader in William Wallace, and Edward's yearly expeditions across the Border called for evermounting taxes, which only increased his difficulties with the barons and the clergy.

Harold, with brothers Frank, Joe and William, took over at the death of their father, Harry M. Stevens, who put a few dollars into a baseball program, introduced the `` hot dog '' and paved the way for creation of a catering empire.

After many years and many interruptions he was able to finish the canopy fresco, and slightly less than half the frieze, beginning with the Liberty group opposite the East door, and ending with William Penn, all but one leg, when a tragic accident ended his career.

She had had a party with a regular visitor, Dr. William W. McClellan.

Early in January, 1844 he had a conference with Henry and William in New Orleans, and upon learning of Gorham's intention, Henry remonstrated calmly but firmly with his brother.

Henry hid his annoyance, although both he and William were furious with their Yankee brother.

William was adamant on one point: under no circumstances would he allow the Negroes to remain on the plantation with his and Henry's slaves if they were told of their coming freedom.

On March 21, 1845 the bark Bashaw weighed anchor at New Orleans, while on the levee Henry and William Palfrey waved farewell to their father's former chattels who must have looked back at the receding shore with mingled regret and jubilation.

William keeps up with our town's doings daily, via the Tribune, and he tells me he never misses the Ticker.

Another speaker, William H. Draper, Jr., former Under Secretary of the Army and now with the Palo Alto venture capital firm of Draper, Gaither & Anderson, urged the U.S. to `` throw down the gauntlet of battle to communism and tell Moscow bluntly we won't be pushed around any more ''.

Among those with reservations are Messrs. and Mmes. William A. Thompson, Van Cott Niven, A. B. Cox, David Bricker, Samuel Perry and Robert D. Stetson.

Published annually by William Hord Richardson, the 1962 edition, subtitled Society Register of Southern California, is scheduled to arrive with Monday morning's postman.

There were two possible methods of breaching the conservative barriers around the Rules Committee: 1 ) to pack it with additional liberals and break the conservative-liberal deadlock, or 2 ) to remove one of the conservatives -- namely Mississippi's 14-term William Meyers Colmer ( pronounced Calmer ).

The Schuman `` Chester '' takes off from an old William Billings tune with rousing woodwind and brass effect.

Mr. Willis, eager to have him allied with the family, wanted advice beyond the confines of his field, and William set out on a serious study of the situation, including trips to Wisconsin and Washington.

William spent a long week end closeted with Hamrick.

Taking Hamrick with him, William went to Mr. Willis.

At the meeting, attended by Freddy, Richert, Herberet and the A-Z executive staff, with Mr. Willis presiding, William and Hamrick did indeed run the gantlet.