Another major breakthrough, whose originators were once thought to be crazy, is the mixing of ethnic cuisines.

A major breakthrough in bridge technology came with the erection of the Iron Bridge in Coalbrookdale, England in 1779.

Alcohol withdrawal can also be a major contributing factor in breakthrough seizures, as well.

A major breakthrough in the development of the modern facsimile system was the result of digital technology.

The industry saw a major breakthrough in 1962 when the government granted the Sociedade de Turismo e Diversoes de Macau ( STDM ), a syndicate jointly formed by Hong Kong and Macau businessmen, the monopoly rights to all forms of gambling.

Charles Thomson, co-founder of the group, described punk as " a major breakthrough " in his art.

This was a major breakthrough as more than a year of political wrangling could not yield an agreement despite pressure from the West and the Arab League.

( The idea of a major breakthrough with FS technology was dropped in the mid-1970s for cost-effectiveness and continuity reasons.

A major breakthrough in the methodology and popularization of volumetric analysis was due to Karl Friedrich Mohr, who redesigned the burette by placing a clamp and a tip at the bottom, and wrote the first textbook on the topic, Lehrbuch der chemisch-analytischen Titrirmethode ( Textbook of analytical-chemical titration methods ), published in 1855.

CL-20 is considered a major breakthrough in solid rocket propellant technology but has yet to see widespread use because costs remain high.

His first major breakthrough came in 1912 at age eighteen with his first book illustration for Carl H. Claudy's Tell Me Why: Stories about Mother Nature.

Pacino made his major breakthrough when he was given the role of Michael Corleone in The Godfather in 1972, which earned him an Academy Award nomination for Best Supporting Actor.

Zeffirelli's major breakthrough came the year after when he presented two teenagers as Romeo and Juliet, the perfect venue for 1968.

Weir's major breakthrough in Australia and internationally was the lush, atmospheric period mystery Picnic at Hanging Rock ( 1975 ), made with substantial backing from the state-funded South Australian Film Corporation and filmed on location in South Australia and rural Victoria.

His breakthrough role was in Jean-Luc Godard's Breathless ( 1960 ), which made him a major figure in the French New Wave.

Well before then, another major breakthrough occurred with the next event registered by BeppoSAX, GRB 970508.

However, the breakthrough came in 1856 when the Declaration of Paris, signed by all major European powers, stated that " Privateering is and remains abolished ".

According to his memoirs written after the war, the German Chief of Staff, Erich von Falkenhayn, believed that although a major breakthrough might no longer be achieved, the French army could still be defeated if it suffered a sufficient number of casualties.

His next major breakthrough came when producer Roy Speer introduced him to leading comic Ted Ray.

But the major breakthrough came the following year when-again under the leadership of Waechter-the Greens polled 10. 6 % in the European parliamentary elections.

As a comparative study it was a major breakthrough at the time.

Sketchpad is considered to be the ancestor of modern computer-aided drafting ( CAD ) programs as well as a major breakthrough in the development of computer graphics in general.

He is credited with the first major breakthrough in heavier-than-air flight and he worked over half a century before the development of powered flight, being acknowledged by the Wright brothers.

A major breakthrough was the introduction of portable defibrillators used out of the hospital.

The major effect of these advances appears to lie in the part they have played in the industrial revolution and in the tools which scientific understanding has given us to build and manipulate a more protective environment.

These basic ideas concerning the nature of religion were, Adams believed, some of the major keys to the understanding of history and the movement of society.

Although we are still far from a complete understanding of these problems, as a first approximation, it is suggested that alterations in the hypothalamic balance with consequent changes in the hypothalamic-cortical discharges account for major changes in behavior seen in various moods and states of emotions in man and beast under physiological circumstances, in experimental and clinical neurosis, and as the result of psychopharmacological agents.

The historian can only point out those lines which were major enough to find reflection in our limited evidence, and must hope that future excavations will enrich our understanding.

Further cultural subdivisions according to tool types, such as Olduwan or Mousterian or Levalloisian help archaeologists and other anthropologists in understanding major trends in the human past.

" The Oriole Way was a belief that hard work, professionalism, and a strong understanding of fundamentals were the keys to success at the major league level.

Deane and J. R. Thomson write this valid conclusion, “ The Book of Obadiah is occupied with one subject – the punishment of Edom for its cruel and unbrotherly love conduct towards Judah ...” One can link this idea of punishment to one of the major prophets “ Ezekiel ” who “... interprets the exile to Babylon and the destruction of Jerusalem as deserved punishments for the sins of those who themselves committed them .” Verses 3-7 in Obadiah explain to the reader the reason for the punishment theme, “ Confidence in one ’ s power, intelligence, allies, or the topographical features of one ’ s territory is often mentioned as an attribute of those who foolishly confront the Lord and are consequently punished .” Although destruction is vital to understanding Obadiah, it is of note to understand the destruction being a consequence of action.

Core concepts are: ( 1 ) That critical social theory should be directed at the totality of society in its historical specificity ( i. e. how it came to be configured at a specific point in time ), and ( 2 ) That critical theory should improve understanding of society by integrating all the major social sciences, including geography, economics, sociology, history, political science, anthropology, and psychology.

In modern times, geology is commercially important for mineral and hydrocarbon exploration and for evaluating water resources ; it is publicly important for the prediction and understanding of natural hazards, the remediation of environmental problems, and for providing insights into past climate change ; plays a role in geotechnical engineering ; and is a major academic discipline.

Recent research in hydrological modeling tries to have a more global approach to the understanding of the behaviour of hydrologic systems to make better predictions and to face the major challenges in water resources management.

Thus three major themes in 19th century mathematics were combined by Lie in creating his new theory: the idea of symmetry, as exemplified by Galois through the algebraic notion of a group ; geometric theory and the explicit solutions of differential equations of mechanics, worked out by Poisson and Jacobi ; and the new understanding of geometry that emerged in the works of Plücker, Möbius, Grassmann and others, and culminated in Riemann's revolutionary vision of the subject.

A major question in understanding language acquisition is how these capacities are picked up by infants from the linguistic input.

A major block to understanding their significance was the importance attached by 19th-century biologists to the apparent blending of inherited traits in the overall appearance of the progeny, now known to be due to multigene interactions, in contrast to the organ-specific binary characters studied by Mendel.

You can gain an understanding of the type of landscape, the location of urban places, and the location of major transportation routes all at once.

By understanding the physical and chemical properties of proteins and other macromolecules at the atomic level in various cells in the kidney, novel therapeutic approaches can be designed to combat major renal diseases.

The field is a major academic discipline, and is also important for mineral and hydrocarbon extraction, knowledge about and mitigation of natural hazards, some Geotechnical engineering fields, and understanding past climates and environments.

Atkinson's work was instrumental in furthering the understanding of the three major phases of the monument's construction.

Systematics is also of major importance in understanding conservation issues because it attempts to explain the Earth's biodiversity and could be used to assist in allocating limited means to preserve and protect endangered species, by looking at, for example, the genetic diversity among various taxa of plants or animals and deciding how much of that to preserve.

Quantum chemistry, the application of quantum mechanics to the understanding of valency, is a major component of theoretical chemistry.

This is in addition to the marking of the occasion at the Vatican's Gregorian University itself and at major centers of Christian-Jewish understanding around the United States.

In more recent times Joseph Kerman, Oliver Neighbour, Philip Brett, John Harley, Richard Turbet, Alan Brown, Kerry McCarthy, and others have made major contributions to increasing our understanding of Byrd's life and music.

A major component of PASSIA ’ s activities is its Roundtable Meetings Program, and with over 100 publications to its credit, many of which include the minutes of these meetings, PASSIA has proved most successful at promoting understanding of international relations as they affect the Palestinian struggle for justice and peace.

* Managing a public-private effort with major segments of the agriculture community and UN agencies for better understanding of the promise, challenge and economics of bioenergy ; and

In the case of Enron, several major banks provided large loans to the company without understanding, or while ignoring, the risks of the company.