So we asked such men in major companies in the design field to offer their opinions on the `` dual-road-up '' problem -- and more importantly -- their solutions.

A well-publicized entrant which has achieved success only recently is the built liquid detergent, with which the major problem today is incorporation of builder and active into a small volume using a sufficiently high builder/active ratio.

Our major problem is what an enemy might accomplish in an initial attack on a target.

However, a major problem here is one of scale of processing ; ;

Hardly a window has been broken since Dunbar first was opened ( and vandalism in schools is a major problem in many slum areas ).

Indeed, the problem of determining the area of plane figures was a major motivation for the historical development of calculus.

In medicine, the major problem of the emergence of resistant bacteria is due to misuse and overuse of antibiotics.

The authors noted an apparent superior efficacy of olanzapine to the other drugs in terms of reduction in psychopathology and rate of hospitalizations, but olanzapine was associated with relatively severe metabolic effects such as a major weight gain problem ( averaging over 18 months ) and increases in glucose, cholesterol, and triglycerides.

The questions can concern anything from a major policy issue to a specific constituent's problem.

This became a major problem as bidding wars between the ballclubs to land the best amateur players escalated signing bonuses.

Another major problem in cosmology is what caused the universe to contain more particles than antiparticles.

The P versus NP problem is a major unsolved problem in computer science.

A major problem in determining whether the Cimbri were speaking a Celtic or a Germanic language is that at this time the Greeks and Romans tended to refer to all groups to the north of their sphere of influence as Gauls, Celts, or Germani rather indiscriminately.

Further, 43 percent of respondents said they use less than half the functionality of their existing system ; 72 percent indicated they would trade functionality for ease of use ; 51 percent cited data synchronization as a major issue ; and 67 percent said that finding time to evaluate systems was a major problem.

Chronic Chagas disease remains a major health problem in many Latin American countries, despite the effectiveness of hygienic and preventive measures, such as eliminating the transmitting insects.

The disease was named after the Brazilian physician and infectologist Carlos Chagas, who first described it in 1909, but the disease was not seen as a major public health problem in humans until the 1960s ( the outbreak of Chagas disease in Brazil in the 1920s went widely ignored ).

In an account that had become standard by the mid-century, Hilbert's problem set was also a kind of manifesto, that opened the way for the development of the formalist school, one of three major schools of mathematics of the 20th century.

Thus far, pyrethroid resistance in Anopheles has not been a major problem.

This prediction came true at least in part: Doom became a major problem at workplaces, both occupying the time of employees and clogging computer networks with traffic caused by deathmatches.

The Stammbaumtheorie proved to be very productive for comparative linguistics, but didn't solve the major problem of studying the origin of language: the lack of fossil records.

In the 21st-century Egypt has encountered a major problem with immigration, as millions of Africans attempt to enter Egypt fleeing poverty and war.

A major problem has been that bacteria do not consume all parts of the malignant tissue.

A major problem at that time was the lack of fossil intermediaries.

Neurocysticercosis, which arises when larvae of the pork tapeworm Taenia solium penetrate the central nervous system, is the major cause of acquired epilepsy worldwide.

This usually arises from a dislodged atherosclerotic plaque in one of the carotid arteries ( i. e. a number of major arteries in the head and neck ) or from a thrombus ( i. e. a blood clot ) in the heart because of atrial fibrillation.

The question of how superconductivity arises in high-temperature superconductors is one of the major unsolved problems of theoretical condensed matter physics.

A major conservation concern for beaked whales ( family Ziphiidae ) is they appear to be vulnerable to modern sonar operations, which arises from recent strandings that temporally and physically coincide with naval sonar exercises.

Bona Vacantia arises, in origin, by virtue of the Royal Prerogative and in some respects this remains the position although the right to bona vacantia of the two major categories is now based on statute: Administration of Estates Act 1925 and the Companies Act 2006.

Hence, once the pheochromocytoma has been resected, thereby removing the major source of circulating catecholamines, a situation arises where there is both very low sympathetic activity and volume depletion.

Convention dictates that a general election should take place roughly three years after the previous general election – unless a major crisis arises or the Prime Minister loses the ability to command a majority in parliament.

A major component of such scum is calcium stearate, which arises from sodium stearate, the main component of soap:

" The major threat to democratic socialism and the major danger of war in Europe arises from Soviet policy and not from American policy ", declared the editors in November 1948.

The major difference arises from the question of whether Henry ( 1394 – 1455 ) was 1st as a new creation or 2nd as a restoration of the rights of his grandfather, Henry ( 1341 – 1408 )

Black's major responses are 3 ... g6 preparing ... Bg7, 3 ... d6 preparing ... Bd7 ( a hybrid line that also arises from the Moscow Variation after 2 ... d6 3. Bb5 + Nc6 ), and 3 ... e6 preparing 4 ... Nge7.

NEXPTIME often arises in the context of interactive proof systems, where there are two major characterizations of it.

The rhomboid major arises from the spinous processes of the thoracic vertebrae T2 to T5 as well as the supraspinous ligament.

22 ), which is only a mild sort of three-key exposition, since the supertonic major is the dominant of the dominant, and commonly arises in any event as part of the modulation.

In machine learning problems, a major problem that arises is that of

The Piako River has two major stems: the main stem arises in the northern slopes of the Te Miro-Tahuroa hills, descending as two distinct tributaries – the Piakonui and the Piakoiti Streams.

A decision can be treated as over-complicated, with too many detailed options, so that a choice is never made, rather than try something and change if a major problem arises.

Another problem which arises is that the same person can abuse his or her power to get away with injustice as exemplified by Bagdikian: " When Sears was accused by the Federal Trade Commission of dishonest advertising and promotion, the Tribune was one of the major papers that failed to carry a word of it ... ( Wardrip-Fruin, 481 ).

The major limitation in higher rates of fire arises due to the problem of heat.

The musculocutaneous nerve arises from the lateral cord of the brachial plexus, opposite the lower border of the Pectoralis major, its fibers being derived from C5, C6 and C7.

It arises from the dorsal surface of the axillary border of the scapula for the upper two-thirds of its extent, and from two aponeurotic laminæ, one of which separates it from the infraspinatus muscle, the other from the teres major muscle.

Regardless, a tendency towards strategic complacency has also been evident, with Australians often reluctant to think about defence issues or to allocate resources until a crisis arises ; a trait which has historically resulted in unpreparedness for major military challenges.

If all the available elements strongly suggest that the star of 1054 was a supernova, and that in the area next to where the star was seen, there is a remnant of a supernova which has all of the characteristics expected of an object that is around 1000 years old, a major problem arises: the new star is described as being to the South-East of Tianguan, while the Crab Nebula is to the North-East.