Apollo succeeded despite the major setback of a 1967 Apollo 1 cabin fire that killed the entire crew during a pre-launch test.

He reformed Austria's armies to adopt the nation at arms principle ; in 1809, he went into the War of the Fifth Coalition with confidence and inflicted Napoleon's first major setback at Aspern-Essling, before suffering a defeat at the bloody Battle of Wagram.

This setback for Parliament in Cornwall, and the last major victory for the Royalists, was reversed by Sir Thomas Fairfax leading the New Model Army at or near Tresillian Bridge, close to Truro on 12 March 1645.

Then a major setback hit the growing business: World War II was well underway and the Canadian government issued wartime rationing regulations.

Charles X had succeeded Louis XVIII in 1824, but in 1827 his party suffered a major electoral setback and by 1830 the opposition liberal party became the majority.

After this major setback, he set sail again on 13 December, aboard Pelican, with four other ships and 164 men.

The first was that of Jesse Gelsinger in 1999, which represented a major setback in the field.

The hurricane of 2008 was a major setback since many bridges in multiple areas was either Collapse or suffers extensive damage ; was in immediate need of repair.

For the Construction of RN7 Canada Pledge US $ 75 and IDB US $ 31 Million for the construction of the road which started in 2009 ; it did suffer major setback because of the earthquake also.

In the 2006 season, Spacey suffered a major setback with a production of Arthur Miller's Resurrection Blues, directed by Robert Altman.

The Battle of Lepanto in 1571 ( which was triggered by the Ottoman capture of Venetian-controlled Cyprus in 1570 ) was another major setback for Ottoman naval supremacy in the Mediterranean Sea, despite the fact that an equally large Ottoman fleet was built in a short time and Tunisia was recovered from Spain in 1574.

Then, in their 17 – 13 loss to the Bills, New York suffered a major setback when starting quarterback Phil Simms went down for the season with a broken bone in his foot.

However, the Bills quest for a third consecutive Super Bowl suffered a major setback when they lost the final game of the season to the Houston Oilers.

This apparent progress in relations suffered a major setback when, in 1959, Nehru accommodated the Tibetan religious leader at the time, the 14th Dalai Lama, who fled Lhasa after a failed Tibetan uprising against Chinese rule.

After the events of Poznań June, they successfully backed the candidature of Władysław Gomułka for First Secretary of party, thus imposing a major setback upon Natolinians.

However, although he remained subject to periods of setback, he eventually recovered sufficiently to write the major works of his later career.

The cause of electoral fusion suffered a major setback in 1997, when the U. S. Supreme Court decided by 6-3 in Timmons v. Twin Cities Area New Party that fusion is not a constitutionally protected civil right.

The group suffered a major setback in a crackdown in 1992 when much of its leadership was neutralized through incarceration.

With slavery abolished, the former slave trader suffered a major financial setback.

Egyptian power in Canaan thus suffered a major setback when the Hittites ( or Hatti ) advanced into Syria in the reign of Amenhotep III, and became even more threatening in that of his successor, displacing the Amorites and prompting a resumption of Semitic migration.

After this setback, a major humiliation for Macmillan's foreign policy, Heath was not a contender for the party leadership on Macmillan's retirement in October 1963.

This was the second major setback the outpost had suffered, and followed severe storms and flooding that had damaged Mission buildings and ruined crops earlier in the year.

France did not as a result receive the promised Nice and Savoy, but Austria did keep Venetia, a major setback for the Piedmontese, in no small part because the treaty had been prepared without their knowledge.

The successful operation against Yassin constitutes a significant blow to a central pillar of the Hamas terrorist organization, and a major setback to its terrorist infrastructure.

His next major work, completed in 1892, was a long fantastic epic in prose, entitled Hans Alienus, which Professor Book describes as a monument on the grave of his carefree and indolent youth.

Trevelyan's Manin And The Venetian Revolution Of 1848, his last major volume on an Italian theme, was written in a minor key.

The weekly loss is partly counterbalanced by 500 arrivals each week from West Germany, but the hard truth, says Crossman, is that `` The closing off of East Berlin without interference from the West and with the use only of East German, as distinct from Russian, troops was a major Communist victory, which dealt West Berlin a deadly, possibly a fatal, blow.

This resulted in an improved appearance, but was followed by an increase in printing cost that necessitated the institution of major economies to keep within the total of allocated funds.

In one of these, an exploding-wire device to study systems thermodynamically up to 6,000 Af and 100 atmospheres pressure, a major goal was achieved.

Along with J. R. Brown's other major developments, the universal grinding machine was profoundly influential in setting the course of Brown & Sharpe for many years to come.

A major consideration in the choice of the Warwick site, four miles from Cranston, was the fact that it permits retention of our present trained and highly skilled work force.

The intimal surface of the aorta was covered with confluent, yellow-brown, hard, friable plaques along its entire course, and there was a marked narrowing of the orifices of the large major visceral arteries.

Supplemental outside reading reports were handled just as in the other sections, the major difference being that there was a noticeably deeper level in the reported outside reading by the married group.

The latest major change in this program was introduced by the National Defense Education Act of 1958, Title 8, of which amended the George-Barden Act.

To free the factors of production was a major objective of the rising bourgeoisie, and this objective required that governmental authority -- administrative officials and judges -- be limited as precisely and explicitly as possible ; ;

This would satisfy what presumably was Congress' major purpose -- the suability of unions.

Service running through Barnumville and to Bennington County towns east of the mountains was in the hands of the `` Gleason Telephone Company '' in 1925, but major supervision of telephone lines in Manchester was with the New England Telephone and Telegraph Company, which eventually gained all control.

But whenever a major purchase was contemplated forty years ago -- a new bedroom set or a winter coat, an Easter bonnet, a bicycle for Junior -- the family set off for the downtown department store, where the selection would be greatest.

Technique pure and simple, rendition, is not of major importance, but it is interesting that Parker, following Lester Young, was one of the leaders of the so-called saxophone revolution.

Since experience indicates that effluents from oxidation ponds do not create major problems at these BOD concentrations, the goal for the effluent quality of the accelerated treatment system was the same as from conventional oxidation ponds.

The major contributor was a shopping center with houses being added to the system as the subdivision developed.

Even though it was known that the Luftwaffe in the north was now being directed by the young and energetic General Peltz, the commander who would conduct the `` Little Blitz '' on London in 1944, a major raid on Bari at this juncture of the war was not to be considered seriously.

The first major change was that of providing wholewheat bread instead of white bread.

The infamous Wansee Conference called by Heydrich in January 1942, to organize the material and technical means to put to death the eleven million Jews spread throughout the nations of Europe, was attended by representatives of major organs of the German state, including the Reich Minister of the Interior, the State Secretary in charge of the Four Year Plan, the Reich Minister of Justice, the Under Secretary of Foreign Affairs.

He finished the war as a major general, commanding a full division, and at 25 was the youngest major general in the history of the U.S. Army.