His political opponent and lifetime friend, Thomas Jefferson, achieved immortality through his authorship of the Declaration of Independence, but equally notable were the legal and constitutional reforms he instituted in his native Virginia, his role as father of our territorial system, and his acquisition of the Louisiana Territory during his first term as President.

The active sponsor of Jefferson's measure for religious liberty in Virginia, Madison played the most influential single role in the drafting of the Constitution and in securing its ratification in Virginia, founded the first political party in American history, and, as Jefferson's Secretary of State and his successor in the Presidency, guided the nation through the troubled years of our second war with Britain.

He went on to say: `` In the first place, industry per se is not dedicated to the role of savior of foundering municipalities.

After another two weeks, the first young emerge, four to eight small daughters that begin to play the role of worker bees, collecting pollen and nectar in the field and caring for the new young generation while the queen retires to a life of egg laying.

They were stressed in the speeches of Si Mubarak Bekkai when the first Council of Ministers was formed and again when the Istiqlal took a leading role in the second Council.

Jen Nelson, as Thea, his first wife, managed to make that short role impressive.

He fired the first shot in defense of Fort Sumter, the opening battle of the war, and had a pivotal role in the early fighting at the Battle of Gettysburg.

Ayckbourn joined Wolfit on tour to the Edinburgh Festival Fringe as an acting assistant stage manager ( meaning a role that involved both acting and stage management ) for three weeks, with his first role on the professional stage being various parts in The Strong are Lonely by Fritz Hochwälder .< ref name = acting >

After moving to Sarov in 1950, Sakharov played a key role in the development of the first megaton-range Soviet hydrogen bomb using a design known as " Sakharov's Third Idea " in Russia and the Teller-Ulam design in the United States.

This musical was Angela Lansbury's first stage musical role.

In 1976 he appeared in his first mainstream film role, in Martin Scorsese's landmark Taxi Driver ; Scorsese allowed Brooks to improvise much of his dialogue.

He played a major role in establishing the University of Pennsylvania and was elected the first president of the American Philosophical Society.

This role was taken in the first two series by Lord Percy Percy, played by Tim McInnerny, with Hugh Laurie playing the role in the third and fourth series, as Prince George, Prince Regent, and Lieutenant George, respectively.

She plays a central role in the first part of G. A. Henty's novel Beric the Briton and in a children's novel by Henry Treece.

* The role of Jim Gordon in Batman Year One being one of the few who doubts that Batman is a threat and is replaced at first by Ethan Bennett.

B. subtilis is the first bacterium for which the role of an actin-like cytoskeleton in cell shape determination and peptidoglycan synthesis was identified, and for which the entire set of peptidoglycan-synthesizing enzymes was localised.

Mumy was reportedly the first choice to portray the role of Eddie Munster in the 1964 situation comedy The Munsters, but his parents objected because of the extensive make-up, and the role instead went to Butch Patrick.

His most famous role was that of The Tramp, which he first played in the Keystone comedy Kid Auto Races at Venice in 1914.

His first role was a newsboy in H. A. Saintsbury's Jim, a Romance of Cockayne.

" But the teenager made an impact on his first night at the London Coliseum, winning more laughs in his small role than the star, and he was quickly signed to a contract.

Love worked with director Alex Cox on her first two films ; she gained a small part in the Sid Vicious biopic Sid and Nancy ( 1986 ), and was then given the leading role in his following film, Straight to Hell ( 1987 ), which caught the attention of artist Andy Warhol.

The Jurchen-founded Jin Dynasty was defeated by the Mongols, who then proceeded to defeat the Southern Song in a long and bloody war, the first war in which firearms played an important role.

Besides its historical significance as a break with the centuries-old tradition of British insularity, Britain's move, if successful, will constitute an historic landmark of the first importance in the movement toward the unification of Europe and the Western world.

Although Mr. Brown was not himself its inventor ( it was a French idea ), it is typical that his intuition first conceived the importance of mass producing this basic tool for general use.

the college was one of the first to recognize the importance of music not only as a definite part of the curriculum but as a vital adjunct to campus life.

All the manuals for setting up vocational courses stress the importance of first making a local survey of skill needs, of estimating the growth of local jobs, and of consulting with local employers on the types of courses and their content.

Even then, the flexibility of the phrasing suggests that the word comes first in importance.

Amino acids having both the amine and carboxylic acid groups attached to the first, or alpha, carbon atom have particular importance in biochemistry.

The first division into major and minor arts dates back to Leon Battista Alberti's works ( De re aedificatoria, De statua, De pictura ), focusing the importance of intellectual skills of the artist rather than the manual skills ( even if in other forms of art there was a project behind ).

Since the first pioneering efforts of Florey and Chain in 1939, the importance of antibiotics, including antibacterials, to medicine has led to intense research into producing antibacterials at large scales.

He wrote that the central theme of the topics above is that of topos theory, while the first and last were of the least importance to him.

Those against the Wild Card see it as diminishing the importance of the pennant race and the regular season, with the true race often being for second rather than first place, while those in favor of it view it as an opportunity for teams to have a shot at the playoffs even when they have no chance of a first-place finish in their division, thus maintaining fan interest later in the season.

The importance of Hankel functions of the first and second kind lies

The Analects stress the importance of ritual, but also the importance of ' ren ', which loosely translates as ' human-heartedness, Confucianism, along with Legalism, is responsible for creating the world ’ s first meritocracy, which holds that one's status should be determined by education and character rather than ancestry, wealth, or friendship.

During the Hellenistic period, the town was of some mercantile importance, although by the first century it had dwindled greatly in size and significance.

However, Judeo-Christian thought also makes an " innovation of the first importance ", Eliade says, because it embraces the notion of linear, historical time ; in Christianity, " time is no longer the circular Time of the Eternal Return ; it has become linear and irreversible Time ".

John Snow, in England, was the first to identify the importance of contaminated water in its cause in 1854.

The first of these shows the importance of women ’ s past contributions to society, and the second strives to teach women of all estates how to cultivate useful qualities in order to counteract the growth of misogyny.

Due to his two periods of exile in 1904 – 1909, to escape the British invasion of 1904, and from 1910 – 1912 to escape a Chinese invasion, he became well aware of the complexities of international politics and was the first Dalai Lama to become aware of the importance of foreign relations.

" Ponet's treatise comes first in a new wave of anti-monarchical writings … It has never been assessed at its true importance, for it antedates by several years those more brilliantly expressed but less radical Huguenot writings which have usually been taken to represent the Tyrannicide-theories of the Reformation ".

The first prominent plan to develop Afghanistan's economy in modern times was the Helmand Valley Authority project, modelled on the Tennessee Valley Authority in the United States, which was expected to be of primary economic importance.

The loss of the Greek originals has given an Armenian translation a special importance ; thus, the first part of Eusebius ' Chronicle, of which only a few fragments exist in the Greek, has been preserved entirely in Armenian, though with lacunae.

The permanent criteria of church structure for the Orthodox Church today, outside the New Testament writings, are found in the canons ( regulation and decrees ) of the first seven ecumenical councils ; the canons of several local or provincial councils, whose authority was recognized by the whole church ; the Apostolic Canons, dating from the 4th century ); and the " canons of the Fathers " or selected extracts from prominent church leaders having canonical importance.

Then, somewhat later that same month, there was a meeting in Washington where the possible importance of the newly discovered phenomenon of fission was first discussed in semi-jocular earnest as a possible source of nuclear power.

They are ( in order of importance, most important first, with notional percentage values.

The book emphasizes what importance Islam has given to manners and etiquette along with the worship of God, citing the traditions of the first four Imams of the Shi ' a Ismaili Fatimid school of thought.