Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost.

Methadone, with its long half-life ( and thus long duration of effect ) and good oral bioavailability, is a common second-choice drug for pain that does not respond to weaker agonists.

One reason for use of Methadone is its advantages for opioid rotation.

Many patients report that Methadone's sedation effect is often less pronounced than with other opioids and cite this as a major argument for preferring Methadone as an analgesic .< ref > Persons reciveing MMT should not suffer from extreme sedation as a resullt of the treatment, due to the fact that a properly prescribed person will have had their dose titrated up to the optimal level to remove the effects of withdrawl, a point at which sedation should not be evident.

Methadone reduction programmes are suitable for addicted persons who wish to stop using drugs altogether.

Some patients will be prescribed as much as 325 mg of methadone a day ; though a dose as low as 30 mg can prove fatal in an opiate naive individual, or in individuals who lack cross-tolerance to other opioids .. Patients prescribed Methadone for pain control, are likely to be given Methadone tablets, that come in the strength of 5mg in the Uk.

Policies on dose reduction vary from clinic to clinic, from a focus on tapering the patient down to a low dose of Methadone so that they can be detoxified completely, to tapering the dose down to less than 10mg so that they are able to abstain completely.

Methadone has traditionally been provided to people who are opiate dependent in a highly regulated methadone clinic, generally associated with an outpatient department of a hospital, though this varies country by country.

Methadone maintenance is rarely covered by private insurance and patients are encouraged to enroll in public welfare programs or face upwards of $ 500 USD per month.

Deaths of persons recieveing Methadone are normally attributable to other factors, such as alcohol or additional drug use on top of the prescribed Methadone.

In the UK, perons who are prescribed oral Methadone can continue to drive after they have satisfactorily completed an independent medical examination which will include a urine screen for drugs.

These medicines are often sold by drug dealers, especially those marked as " CD POM ," which are controlled due to abuse risk such as Diconal, Temazepam, and Methadone.

In chronic pain conditions that are opioid responsive a combination of a long-acting ( Oxycontin, MS Contin, Opana ER, Exalgo and Methadone ) or extended release medication is often prescribed in conjunction with a shorter-acting medication ( oxycodone, morphine or hydromorphone ) for breakthrough pain, or exacerbations.

Methadone and buprenorphine are maintenance therapies intended to reduce cravings for opiates, thereby reducing illegal drug use, and the risks associated with it, such as disease, arrest, incarceration, and death, in line with the philosophy of harm reduction.

* The Trench Methadone Clinic and the David Trench Rehabilitation Clinic, both in Hong Kong, are named after him.

Methadone clinics are only for recovering addicts from opiates.

Methadone can provide a method of stable treatment of the symptoms associated with withdrawal and mental anguish, and, with a proper slow taper, can be discontinued after the patient feels he or she is ready, often after a year or more, which gives the addict time to get away from old habits or triggers.

Methadone pills often contain talc that, when injected, produces a swarm of tiny solid particles in the blood, causing numerous minor blood clots.

In the UK, when a prescriber of Methadone uses form FP10 for the daily dispensing of the drug, the name of the allocated pharmacy that the user must go to is included.

Other substances can reduce the metabolism of Methadone and in such a situation, a patient who fared fine after the first few doses could reach high levels of the drug in his body without ever taking more than was prescribed.

) Methadone Anonymous is similar to NA, but considers the use of methadone to be a tool of recovery and not a drug.

Tajzadeh has written several letters from prison which have angered the authorities who have in turn put him inside Evin Prison's Methadone Ward, a ward generally reserved for hardcore criminals and drug addicts.

Methadone is considered a very helpful drug for people that use the drug the way it is prescribed.

* Methadone treatment program, a form of treatment for heroin addiction

Methadone ( also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names ) is a synthetic opioid, used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency.

However, Methadone has much lower cross-tolerance, when switching to it from other opioids, than other opioids .< ref > This means that Methadone can start at a low dose, and the time for the next switch will be longer.

Injecting Methadone pills can cause collapsed veins, bruising, swelling, and possibly other harmful effects.

Methadone clinics operate as any other addiction medical facility.

** Phenylpiperidine derivative Opioids: Meperidine / Pethidine, Tramadol, Methadone, Fentanyl, Dextropropoxyphene, Propoxyphene.

Methadone was introduced into the United States in 1947 by Eli Lilly and Company.

Methadone is mainly used in the treatment of opioid dependence.

Methadone is approved for different indications in different countries.

The treatment of opiate addicted persons with Methadone will follow one of two routes.

When used correctly, Methadone maintenance has been found to be medically safe and non-sedating.

After a patient has been on a maintenance programme for a period, they will be offered the opportunity to move over to a Methadone reduction programme.

When an individual is leaving the UK with an amount of Methadone that exceeds 500mg, a Home Office Export Licence is required which should be arranged by the prescriber.

This licence allows the individual to export the licenced amount and import any remaining Methadone that has not yet been used. The granting of a licence does not guarentee that the Methadone or person will be allowed entrance into the country of travel.

Individuals who intend to undertake overseas travel should make contact with the embassy of the intended destination to arrange for the importation of the Methadone.

Methadone clinics in the U. S. charge anywhere from $ 5 – 400 per week, which may be covered by private insurance or Medicaid.

In the early months of 1714, the battle between Swift and Steele over the issue of the Succession entered its major phase.

For here if anywhere in contemporary literature is a major effort to counterbalance Existentialism and restore some of its former lustre to the tarnished image of the species Man, or, as Malraux himself puts it, `` to make men conscious of the grandeur they ignore in themselves ''.

Mr. Speaker, I rise today to pay tribute to a great newspaper, the New York Times, on the occasion of a major change in its top executive command.

The company is still broadening its line and is now active on four major fronts.

In addition to its major effort on fuel cells, Patterson Moos Research Division is continuing to carry on research in other fields, both under contract for the Defense Department, other government agencies and for our own account.

The site may be on one of the major flyways of migratory birds or have its own resident bird life.

For this first development the supplier signing the lease is a major oil company but in turn the deal is being transferred for operation to its local fueloil distributor.

The intimal surface of the aorta was covered with confluent, yellow-brown, hard, friable plaques along its entire course, and there was a marked narrowing of the orifices of the large major visceral arteries.

Each year from 1941 on, its medical staff had conducted intensive field investigations to determine changes in population structure and vital rates and, as its primary objective, the incidence of major diseases.

Most of us remember and think of the Wagner-Peyser Act in its historical sense, as a major milestone in the development of public placement services.

Of course, nationalism has really outlived its usefulness in a country as world-oriented as ours, and its continued existence reflects one of the major culture lags of the twentieth-century United States.

He suggested that without the Socialist Party ever gaining a national victory, most of its original program has come to pass under both major parties.

Indeed, the administration's curious position on the sales tax was a major factor in contributing to its defeat.

It is natural that he should turn for his major support to a select and dedicated few from the organization which actually owns the university and whose goals are, in their opinion, identified with its highest good and ( to use that oft-repeated phrase ) ' the attainment of excellence ' ''.

The Nassau system recognizes that its major task it to broaden reference service, what with the constant expansion of education and knowledge, and the pressure of population growth in a metropolitan area.

Another major church body had 4,499,608 members and twenty years later its membership stood at 4,622,444.

Genetically speaking, the aardvark is a living fossil, as its chromosomes are highly conserved, reflecting much of the early eutherian arrangement before the divergence of the major modern taxa.

Nobel also owned Bofors, which he had redirected from its previous role as primarily an iron and steel producer to a major manufacturer of cannon and other armaments.

* 1865 – American Civil War: The Battle of Sayler's Creek – Confederate General Robert E. Lee's Army of Northern Virginia fights its last major battle while in retreat from Richmond, Virginia.

During its preparation he became a friend of Cosima Wagner ( then in Strasbourg ), with whom he had many theological and musical conversations, exploring his view of Bach's descriptive music, and playing the major Chorale Preludes for her at the Temple Neuf.

Azerbaijan is an economy that has completed its post-Soviet transition into a major oil based economy ( with the completion of the Baku-Tbilisi-Ceyhan Pipeline ), from one where the state played the major role.

It has two main features on which its distinction as a major contribution to Avicennan studies may be said to rest: the first is its clarity and readability ; the second is the comparative approach adopted by the author [...].