# Opioids, particularly methadone, are particularly effective treatments for the symptoms of severe RLS and do not have the negative side-effects ( augmentation and rebounding ) of dopamine agonists.

Opioids which have other neurotransmitter impacts such as tramadol, pethidine, & c. can also cause jerks, but unlike the above are not completely benign.

Opioids such as morphine are not used as the primary medicine since they are not effective sedative medications compared to benzodiazepines.

Opioids are known to have strong antidepressive, anxiolytic and antipsychotic effects and thus opioid dependence often develops as a result of self medication.

Opioids alone or opioids with adjunctive medication ( either a local anesthetic or clonidine ) or more recently ziconotide are infused.

Opioids, the class of pain-reducing substances which include morphine, heroin, and hydrocodone, are anaphrodisiacs.

Opioids are painkillers.

Opioids, while very effective analgesics, may have some unpleasant side-effects.

* Opioids ' classical use besides pain relief is as an anti-diarrhoeal drug.

Opioids and opiate receptors occur naturally in crustaceans and, although at present no certain conclusion can be drawn, their presence indicates that lobsters may be able to experience pain.

Opioids may mediate their pain in the same way as in vertebrates.

*** Opioids provide more potent pain control and the weaker members such as codeine may be available over the counter in combination with paracetamol ( co-codamol ).

Opioids work in the modulation of pleasure or pain relief by either blocking neurotransmitter release or by hyperpolarizing neurons by opening up a potassium channel which effectively temporarily blocks the neuron.

** Opioids activate or block opioid receptors in the brain typically to reduce the effect of pain.

Opioids were used to treat major depression until the late 1950s.

Opioids have agonist actions on the intestinal opioid receptors, which when activated cause constipation.

Opioids also may act on the gut indirectly through tonic gut spasms after inhibition of nitric oxide generation.

** Phenylpiperidine derivative Opioids: Meperidine / Pethidine, Tramadol, Methadone, Fentanyl, Dextropropoxyphene, Propoxyphene.

" Opioids: Past, Present and Future.

Opioids include heroin ( diacetylmorphine, not used in medicine in most countries ), oxycodone, hydromorphone, hydrocodone ( Vicodin ), fentanyl, pethidine, tramadol and others.

Opioids can fragment sleep and decrease REM and stage 2 sleep.

Opioids such as morphine and heroin do not cause pupil dilation.

Opioids inhibit GABA release ; this decreases the amount of inhibition and allows them to fire spontaneously.

Opioids requiring Cytochrome P-450 activation ( e. g. codeine, dihydrocodeine ) should perhaps be used with an agent not chemically related to the SSRIs ; conversely, they may impact parts of the Liberation, Absorption, Distribution, Metabolism & Elimination profile for morphine, hydromorphone, oxymorphone & c the other way.

Opioids and anaesthetic drugs tend to depress ventilation, especially with regards to carbon dioxide response.

For more information on the palliative care use of sedatives and the safe use of opioids see Opioids.

Opioids inhibit the firing of neurons in the locus coeruleus.

And by definition sacraments are " efficacious signs of grace, instituted by Christ and entrusted to the Catholic Church, by which divine life is dispensed to us.

The sufferings of Christ's life as well as of the crucifixion are efficacious to redemption.

Magic often utilizes symbols that are thought to be intrinsically efficacious.

These objects and events are said to be intrinsically efficacious, so that the supernatural is unnecessary.

group they are no more efficacious, do not improve specific symptoms, have no clearly different side-effect profiles than the first-generation antipsychotics, and are less cost effective.

" In areas where doxycycline and mefloquine are equally efficacious in preventing malaria, doxycycline is the drug of choice.

When administered alone sulfonamides are not efficacious in treating malaria but co-administration with the antifolate pyrimethamine, most commonly as fixed-dose sulfadoxine-pyrimethamine ( Fansidar ), produces synergistic effects sufficient to cure sensitive strains of malaria.

While folk practices like hoodoo are trans-cultural phenomena, what is particularly innovative in this tradition is the " remarkably efficacious use of biblical figures " in its practices and in the lives of its practitioners.

Peppermint oil has been traditionally used as an antispasmodic, and a review of studies on the topic found that it " could be efficacious for symptom relief in IBS " ( as an antispasmodic ) although more carefully controlled studies are needed.

Sincerely observing the natural law and its precepts inscribed by God on all hearts and ready to obey God, they live honest lives and are able to attain eternal life by the efficacious virtue of divine light and grace since God who clearly beholds, searches, and knows the minds, souls, thoughts, and habits of all men, because of His great goodness and mercy, will by no means suffer anyone to be punished with eternal torment who has not the guilt of deliberate sin. He saw their situation as different from that of people " living in error and alienated from the true faith and Catholic unity … stubbornly separated from the unity of the Church and also from the successor of Peter, the Roman Pontiff ," namely those of whom the Second Vatican Council said, as quoted above: " They could not be saved who, knowing that the Catholic Church was founded as necessary by God through Christ, would refuse either to enter it or to remain in it.

CCBs are particularly efficacious in treating elderly patients.

These are generally efficacious and have the advantage of not restricting patients ' movements or caregivers ' ability to examine the patients as significantly as an iron lung does.

H. G. de Willmott Newman ( Mar Georgius I ) felt that all proper and valid consecrations and ordinations are equally efficacious regardless of the particular line of Apostolic Succession, but also that some degree of irregularity would attach itself to acts lacking ecumenical sanction.

Despite their well-established efficacy, indications for monoamine oxidase inhibitors are currently very limited, due to their significant potential for adverse effects, many interactions, and the availability of newer and safer ( although not necessarily more efficacious ) antidepressants.

The Celtic and Germanic peoples are believed to have eaten the black salsify, which was considered efficacious against the bubonic plague and snake bites until the 16th century.

SSRIs include fluoxetine, paroxetine, sertraline and citalopram and are not recommended to treat painful neuropathy because they have been found to be no more efficacious than placebo in several controlled trials.

If follows, therefore, that if upon examination you find those new doctrines which are now preached to us better and more efficacious, we should immediately receive them without any delay.

Although modeling techniques for prediction of binding affinity are reasonably successful, there are many other properties, such as bioavailability, metabolic half-life, lack of side effects, etc., that first must be optimized before a ligand can become a safe and efficacious drug.

The notion that mental states are causally efficacious diverges from behaviorists like Gilbert Ryle, who held that there is no break between cause of mental state and effect of behavior.

Connectionism is a recent applied approach to artificial intelligence that often accepts a lot of the same theoretical framework that LOTH accepts ; that mental states are computational and causally efficacious and very often that they are representational.

There are no good studies, however, comparing cryosurgery with other modalities, particularly with Mohs surgery, excision, or electrodesiccation and curettage so that no conclusion can be made whether cryosurgery is as efficacious as other methods.