The extinction of the Medici dynasty and the accession in 1737 of Francis Stephen, duke of Lorraine and husband of Maria Theresa of Austria, led to Tuscany's temporary inclusion in the territories of the Austrian crown.

* August 26 – A conspiracy against Piero di Cosimo de ' Medici, led by Luca Pitti and Borso d ' Este, is discovered and put down in Florence.

Clement frequently changed his alliances between the Empire and France, which eventually led him to marry off his first cousin, twice removed, Catherine de ' Medici, to the son of Francis I of France, the future Henry II of France.

As the populace took to the streets to expel Piero, the late Lorenzo de ’ Medici ’ s son and successor, Savonarola led a delegation to the camp of the French king.

Mismanagement of the kingdom and ceaseless political intrigues by Marie de Medici and her Italian favourites led the young king to take power, in 1617, by exiling his mother and executing her followers, including Concino Concini, the most influential Italian at the French court.

The popular unrest caused by the assassination, coupled with the city of Orléans ' resistance to the siege, led Catherine de ' Medici to mediate a truce, resulting in the Edict of Amboise ( 1563 ).

The mediation of Catherine de ' Medici led to the Edict of Union, in which the crown accepted almost all the League's demands ; reaffirming the Treaty of Nemours, recognizing Cardinal de Bourbon as heir, and making the duke of Guise Lieutenant-General.

His poor handling of the situation and failure to negotiate better terms led to an uproar in Florence, and the Medici family fled.

D ' Avalos captured the French outpost at Sant ' Angelo, cutting the lines of communication between Pavia and Milan, while a separate column of landsknechts advanced on Belgiojoso and, despite being briefly pushed back by a raid led by Medici and Bonnivet, occupied the town.

Titian's equestrian portrait of Charles V, Holy Roman Emperor of 1548 led the way in applying the form to rulers, and Cosimo I de ' Medici by Giambologna in Florence ( completed 1598 ) is the first life-size statue to feature a ruler rather than a condotiere.

This alleged promise led to bitter scenes of jealousy and arguing at the court when shortly afterwards Henry married Marie de ' Medici instead.

On one occasion, he informed to the Grand Duke Francesco on two lovers in the Medici household — Eleonora, the wife of Pietro de ' Medici, who was having an illicit affair with Bernardino Antinori — and his informing led directly to Eleonora's murder by Pietro.

In 1607 her composition of a Carnival entertainment entitled La stiava seems to have led to her hiring as a musician in the service of the Medici court.

In their 2006 book, The Medici Conspiracy: The Illicit Journey of Looted Antiquities -- From Italy's Tomb Raiders to the World's Greatest Museums, Peter Watson and Cecelia Todeschini lay out the dynamics of the illegal trade in antiquities and use Leon Levy and Shelby White as an example of collectors whose purchases may have led to unethical dealing in artifacts.

The severity of the sack of Prato led to the surrender of the Florentine Republic, and to the restoration of the Medici rule.

Dodge's role in the preservation and patronage of art disallowed by the government led to his being called " the Lorenzo de ' Medici of Russian art " ( Elena Kornetchuk in Mcphee 1994 ).

He continued under the patronage of the Medici, when together with the sculptor Ercole Ferrata, Ferri the painter led the Medici Academy in Rome, established in 1673 by Grand Duke Cosimo III of Tuscany.

John led the chase after her and the other dogs strung out behind, many of them trailing blood.

The injustice of the ruling later led to a change in California law to allow blood tests as evidence.

Joseph von Mering and Oskar Minkowski made the observation in 1889 that removing the pancreas surgically led to an increase in blood sugar, followed by a coma and eventual death — symptoms of diabetes mellitus.

Himmler's belief that " it is in the nature of German blood to resist " led to his conclusion that Balts or Poles who resisted Germanization were racially superior to more compliant ones.

* 1921 – Researchers at the University of Toronto led by biochemist Frederick Banting prove that the hormone insulin regulates blood sugar.

Next two young patrician Luperci were led to the altar, to be anointed on their foreheads with the sacrificial blood, which was wiped off the bloody knife with wool soaked in milk, after which they were expected to smile and laugh.

This life he led for many months, saying that he had taken up an art that was without muscles, foreshortening or perspective and, better still, without faultfinding, and that the art that he had given up imitated flesh and blood, but this one created flesh and blood ; in this if you had good wine you heard yourself praised, but in that every day you were blamed.

He invented the precursor technique to Gram staining bacteria, and the methods he developed for staining tissue made it possible to distinguish between different type of blood cells, which led to the capability to diagnose numerous blood diseases.

" At his burial a thousand men, in files, preceded the corpse, which was adorned with bunches of rosemary dipped in blood ; on each side rode three trumpeters, and behind was led the trooper ’ s horse, covered with mourning ; some thousands of men and women followed with black and green ribbons on their heads and breasts, and were received at the grave by a numerous crowd of the inhabitants of London and Westminster.

Prayer, example, and penance enable the church to exercise a true motherhood toward all souls who are to be led to Christ, irrespective of nationality, blood, or time.

This led to Harvey's estimate that about of blood went through the heart every time it pumped.

This led Harvey to believe that the veins allowed blood to flow to the heart, and the valves maintained the one way flow.

This led to the civil war called the Kin-strife, when Eldacar, a man of mixed descent and the rightful heir to the throne, was challenged by Castamir, who was of pure Dúnedain blood.

Heatley's blood alcohol content was below the legal limit, but his combination of speeding ( he was driving an estimated 80 miles per hour ) and recklessness led to criminal charges, which were later dropped.

In 1877, during the Russian-Turkish War, a mission from the Samara city government Duma led by Pyotr V. Alabin, as a symbol of spiritual solidarity, brought a banner tailored in Samara pierced with bullets and saturated with the blood of both Russians and Bulgarians, to Bulgaria, which has become a symbol of Russian-Bulgarian friendship.

Insulin was thought to control the metabolism of sugar ; its lack led to an increase of sugar in the blood which was then excreted in urine.

The act eventually led to Heracles ' own death, as Deianeira, fearing that Heracles loved Iole more, gave Heracles a robe smeared with the blood of the Centaur Nessus, believing it was a love-charm.

Their last common ancestor had at most a very simple photoreceptive spot, but a range of processes led to the progressive refinement of this structure to the advanced camera eye — with one subtle difference: The cephalopod eye is " wired " in the opposite direction, with blood and nerve vessels entering from the back of the retina, rather than the front as in vertebrates.

These findings have led to the hypotheses that ( 1 ) breakdown of the blood – brain barrier allows access of neuron-binding autoantibodies and soluble exogenous Aβ42 to brain neurons and ( 2 ) binding of these auto-antibodies to neurons triggers and / or facilitates the internalization and accumulation of cell surface-bound Aβ42 in vulnerable neurons through their natural tendency to clear surface-bound autoantibodies via endocytosis.

In 1171, Blois was the site of a blood libel accusation against its Jewish community that led to 31 Jews ( by some accounts 40 ) being burned to death.

In the myth, Sekhmet's blood-lust was not quelled at the end of battle and led to her destroying almost all of humanity, so Ra had tricked her by turning the Nile as red as blood ( the Nile turns red every year when filled with silt during inundation ) so that Sekhmet would drink it.

In fact, studies involving mutation of genes coding for protein A resulted in a lowered virulence of S. aureus as measured by survival in blood, which has led to speculation that protein A-contributed virulence requires binding of antibody Fc regions.

Her impact in the zing commercials had led to her being considered for an excellent part in an upcoming TV series, Underwater Western Eye, a documentary-type show to be sponsored by Oatnut Grits.

The popularity of CCD imaging among amateurs has led to large numbers of web sites being written by individuals about their images and equipment.

This led to experienced players being able to play indefinitely on a single credit.

" Österreichische Kanzleisprache " is now used less and less, thanks to various administrative reforms which have led to there being fewer of the classic civil servants, the Beamter.

This led to americium being located right below its twin lanthanide element europium ; it was thus by analogy named after another continent, America: " The name americium ( after the Americas ) and the symbol Am are suggested for the element on the basis of its position as the sixth member of the actinide rare-earth series, analogous to europium, Eu, of the lanthanide series.

Azincourt is famous as being near the site of the battle fought on 25 October 1415 in which the army led by King Henry V of England defeated the forces led by Charles d ' Albret on behalf of Charles VI of France, which has gone down in English history as the Battle of Agincourt.

This led to many townlands being recorded as having two names during the 1824 Ordnance Survey, and some maps today give different names for the same place.

MCC ’ s wish for it to be seen by as wide a range of cricket enthusiasts as possible has led to its being mistaken for an official trophy.

The ruthless and belligerent Armstrong led his team back to England in 1921 where his men lost only two games late in the tour to narrowly miss out of being the first team to complete a tour of England without defeat.

However, much of southeastern Europe and central Europe, including many of the Goths and Vandals respectively, had embraced Arianism ( the Visigoths converted to Arian Christianity in 376 ), which led to Arianism being a religious factor in various wars in the Roman Empire.

The situation became unstable and, in the following year, being led by what he afterwards discovered to be false representations, Afonso declared Peter a rebel and defeated his army in the Battle of Alfarrobeira, in which his uncle ( and father-in-law ) was killed.

Her Latin origins and culture however led to creeping resentment from her Greek subjects ( who felt insulted enough by the late Manuel's Western tastes, let alone being ruled by his Western wife ), building up to an explosion of rioting that almost became a full civil war.

The manuscript, which is being edited for publication by G. Maltsiniotis, later led to another of his monumental works, Les Dérivateurs.

Adorno concluded that astrology was a large-scale manifestation of systematic irrationalism, where individuals were subtly being led to believe that the author of the column was addressing them directly through the use of flattery and vague generalizations.

However, the need to engage targets at night, in depth or hit the target with the first rounds quickly led to predicted fire being developed in World War I.

Abigail's self-styling as a handmaid led to Abigail being the traditional term for a waiting-woman, for example as the waiting gentlewoman in Beaumont and Fletcher's The Scornful Lady, published in 1616.

In contrast to the largely alignment-oriented statistically led methods of Green archaeoastronomy, Brown archaeoastronomy has been identified as being closer to the history of astronomy or to cultural history, insofar as it draws on historical and ethnographic records to enrich its understanding of early astronomies and their relations to calendars and ritual.

One event that affected ` Abdu ' l-Bahá greatly during his childhood was the imprisonment of his father when ` Abdu ' l-Bahá was eight years old ; the imprisonment led to his family being reduced to poverty and being attacked in the streets by other children.

However, the Hotaki dynasty came to a complete end in 1738 after being toppled by the Afsharids who were led by Nader Shah of Khorasan.

A general wind-down of the budget led to it being cancelled in 1997.

This in turn has led to the thought that " being " and nothingness are closely related, developed in existential philosophy.

It was subsequently discovered that the BCG administered had been contaminated with a virulent strain that was being stored in the same incubator, and led to legal action being taken against the manufacturers of BCG.