Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon being appointed Prime Minister of Italy, Mussolini had to form a coalition government, because the Fascists did not have control over the Italian parliament.

Upon the outbreak of war the RAN's focus shifted to supporting the coalition land forces and clearing the approaches to Iraqi ports.

Upon appointment, Cowen formed the 28th Government of Ireland out of a coalition of Fianna Fáil, the Green Party, the Progressive Democrats, and initially three independent TDs.

Upon the formation of the coalition ministry between the Whigs and the Peelites, in 1853, under Lord Aberdeen, Lord Clarendon became Secretary of State for Foreign Affairs.

Upon the resignation of the Social Democrats from the government in June 1920 as a result of their poor showing in the elections of that year, Fehrenbach became Chancellor of Germany, forming a coalition with the left-wing liberal DDP and the national-liberal DVP.

Upon his arrival, Mujib met with Bhutto and both agreed to form a coalition government with Mujib as premier and Bhutto as president.

Upon being elected, Jón announced that he would not enter a coalition government with anyone that had not watched the HBO series The Wire.

Upon the resignation of Chancellor Ludwig Erhard on 1 December 1966, a grand coalition of Christian Democrats and Social Democrats had governed West Germany under Federal Chancellor Kurt Georg Kiesinger ( CDU ) with SPD chairman Willy Brandt as vice-chancellor and foreign minister.

Upon the following 1920 election, the CS gained 41. 8 % of the votes cast surpassing the Social Democrats and as the strongest party entered into a right-wing coalition with the newly established nationalist Greater German People's Party ( GDVP ).

Upon leaving AO Talon, Iraqi Army Units were on the verge of operating independently of coalition forces and capable of executing security and civil military operations.

Upon his return to England he was fined £ 400 for his actions, although by that time Pitt was already very wealthy and could easily afford the fine.

His demo for the song " Man Talk ", which would finally appear on the album ... Upon My Wicked Son, was featured in the early Brad Pitt film Cutting Class as well as other unreleased Wall of Voodoo demos.

Upon receiving the evidence of al-Ala's defeat in al-Andalus, al-Mansur is said to have gasped, “ God be praised for placing a sea between us ”!

Upon his return, the Buddha says, among other things, that Pasenadi is " a friend of virtue, acquainted with virtue, intimate with virtue ", while the opposite is said of the aggressor, King Ajatasattu.

The company said " Upon additional analysis of the business jet market related to this product offering, we decided to formally cancel further development of the Citation Columbus ".

Upon presenting the painting to the convention, he said " Citizens, the people were again calling for their friend ; their desolate voice was heard: David, take up your brushes .., avenge Marat ...

In his Essay Upon Several Subjects Concerning British Antiquities, written just after the Jacobite rising of 1745 he described how the politics of Scotland were not based on loyalty to Kings or Queens as Jacobites had said but on royal land grants given in return for loyalty.

Upon accepting the book for publication Santillana said, " It is my understanding that, fictional as the material may sound, it is straight autobiography.

Upon encountering the lifeless body of King Louis, Suleiman is said to have lamented: " I came indeed in arms against him ; but it was not my wish that he should be thus cut off while he scarcely tasted the sweets of life and royalty.

Upon penetration, the oocyte is said to have become activated.

Upon his abdication, King Prajadhipok said that the duty of a ruler was to reign for the good of the whole people, not for a selected few.

Upon the 5 a. m. sunrise, reportedly a train whistle was heard ( HIrsch said it was actually a siren ).

Upon arrival she is said to have been upset by the discrimination against Black Americans.

Upon signing, Bergkamp said Inter " met all my demands.

Upon being notified of receiving this honor, Simon said, “ I am grateful to be the recipient of the Gershwin Prize and doubly honored to be the first.

Upon receiving the knighthood from the Queen at Buckingham Palace on 1 December 2005, he said he was " humbled " by the " fantastic tribute ".

Upon his defeat, Tilden said, " I can retire to public life with the consciousness that I shall receive from posterity the credit of having been elected to the highest position in the gift of the people, without any of the cares and responsibilities of the office.

Upon finding him, Muybridge said, " Good evening, Major, my name is Muybridge and here's the answer to the letter you sent my wife ", and shot him pointblank.

Upon the death of his stepfather, Neipperg, and the revelation that his mother had borne two illegitimate children to him prior to her marriage, Franz said to his friend, Prokesch von Osten, "' If Josephine had been my mother, my father would not have been buried at Saint Helena, and I should not be at Vienna.

Upon the release of " Sorted for E's and Wizz ", the Daily Mirror printed a front-page story headed " BAN THIS SICK STUNT " alongside a story by Kate Thornton which said the song was " pro-drugs " and called for the single to be banned.

Upon this request it is said that Lord Krishna opens his mouth in front of Yashoda who sees the Seven Oceans, the entire Universe with its vast expanse and also Lord Narayana seated upon Adishesha ( The Divine Snake ), attended upon by his beloved consort Mahalakshmi.

Upon seeing the officers and Allen Crum, Mike gestured to the observation deck and said: " He's out there.

Upon his death, it is said that the great number of crickets he kept at Newstead left the estate in swarms.

Upon learning the tooth fairy is not real, 75 % of children reported liking the custom ; 20 % were neutral and 3 % were not in favor and said they did not intend to continue the practice when they became parents.

Upon his return to France, it is said that Lafayette became involved in an affair with the comtesse Aglaé d ' Hunolstein, one that he broke off on 27 March 1783 by letter, at the insistence of her family.