Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

In the 2002 Sight and Sound Directors ' Poll, Pollack revealed his top ten films: Casablanca, Citizen Kane, The Conformist, The Godfather Part II, Grand Illusion, The Leopard, Once Upon a Time in America, Raging Bull, The Seventh Seal, and Sunset Boulevard.

Upon moving by the Outer Banks, a storm surge of up to 6 feet ( 1. 8 m ) occurred on the Pamlico Sound side of Buxton and Ocracoke Village.

Upon his retirement, he owned and operated Paul Berlenbach's Ringside Restaurant in Sound Beach, New York in the 1950's.

Upon release of the New Sound Theory series executive-produced by the pair, local DJ ’ s participated in “ New Sound Sundays ” held weekly at Halo Lounge in Atlanta, hosted by their record label basicLUX Records.

Recent performances have included FAME ( 2002 ), How to Succeed in Business Without Really Trying ( 2003 ), Once Upon a Mattress ( 2004 ), Grease ( 2005 ), The Sound of Music ( 2006 ), The Wizard of Oz ( 2007 ), Footloose ( 2008 ), Crazy For You ( 2009 ), The Music Man ( 2010 ), Peter Pan ( 2011 ), and Back to the 80s ( 2012 ).

Upon arriving at the rim of North Ray Crater, they were away from the LM.

Upon antigen binding, they cluster in large patches, which can exceed 1 micrometer in diameter, on lipid rafts that isolate the BCRs from most other cell signaling receptors.

“ Upon her children I will have no pity, because they are children of whoredom ” ( Hosea 2: 4 ).

Upon his ejection, Mr. Sianis uttered, " The Cubs, they ain't gonna win no more.

Upon reaching Salzburg, however, they found that he was not available and, disillusioned, returned to the United States after spending only 15 days of their planned three years in Europe.

Upon arriving at Archduke Franz Ferdinand's country seat, château Konopiště, on a semi-official visit, they promptly proceeded to do away with one of the Austro-Hungarian heir presumptive's priceless golden pheasants, thereby almost causing an international incident.

Upon further examination, it was concluded that if the marks were bite marks, they did not match the teeth of any of the three convicted.

Upon observation, researchers discovered users unconsciously assuming ELIZA's questions implied interest and emotional involvement in the topics discussed, even when they consciously knew that ELIZA did not simulate emotion.

Upon his arrival in Hollywood, Lang joined the MGM studio and directed the crime drama Fury, starring Spencer Tracy as a man wrongly accused of a crime and then attacked by lynch mob who burn down the jail where he is awaiting trial and it is assumed they killed him in the flames, but did not.

Upon reaching the Cap Rock section of the park, they attempted to cremate Parsons ' corpse by pouring five gallons of gasoline into the open coffin and throwing a lit match inside.

" Upon completing, they may stop collecting, expand the collection to include related items, or begin an entirely new collection.

Upon his return to the astronaut corps in Houston, he played a key role in training Apollo crews to be geologic observers when they were in lunar orbit and competent geologic field workers when they were on the lunar surface.

Upon examining DNA from the moa, they believe that the kiwi is more closely related to its Australian cousins.

Upon reusing these healthy chickens, Pasteur discovered he could not infect them, even with fresh bacteria ; the weakened bacteria had caused the chickens to become immune to the disease, though they had caused only mild symptoms.

Upon gaining 75 % pass marks, they can proceed to the next level.

Upon seeing a chemist's shop, Cleese pondered whether the shop would sell cheese, to which Chapman responded that if they did it would be medicinal cheese and that Cleese would need a prescription to buy some.

Upon arriving in Diriyah, Muhammad bin Saud and Muhammad ibn ʿAbd al-Wahhab concluded an agreement that, together, they would bring the Arabs of the peninsula back to the " true " principles of Islam as they saw it.

Upon Escher's death, his three sons dissolved the Foundation, and they became partners in the ownership of the art works.

Upon the Spaniards ' arrival to the Philippines, they were dismayed to find such a strong Muslim presence on the island, having just expelled the Moors from Spain after centuries of fighting.

Upon leaving the White House, the couple returned to California, where they purchased a home in the wealthy East Gate Old Bel Air neighborhood of Bel Air, Los Angeles, dividing their time between Bel Air and the Reagan Ranch in Santa Barbara, California ; Ronald and Nancy regularly attended Bel Air Presbyterian Church as well.

Upon their arrival in Puerto Rico, they were received by 18, 000 people.

* Upon calling the athlete's name, they have sixty seconds to commence the throwing motion.

Upon activation, they assign proteins to specific membrane subdomains where they participate in signaling.