If a receptor tyrosine kinase ( RTK ) is involved in activating the pathway, the isozyme PLC-γ has tyrosine residues that can become phosphorylated upon activation of an RTK, and this will activate PLC-γ and allow it to cleave PIP < sub > 2 </ sub > into DAG and IP < sub > 3 </ sub >.

If the cell does not lose its signal through the ITAM pathway, it will continue down-regulating CD8 and become a CD4 < sup >+</ sup >, single positive cell.

If the current has a direct pathway to the heart ( e. g., via a cardiac catheter or other kind of electrode ), a much lower current of less than 1 mA ( AC or DC ) can cause fibrillation.

If a coagulation factor is part of the contact activation or tissue factor pathway, a deficiency of that factor will affect only one of the tests: Thus hemophilia A, a deficiency of factor VIII, which is part of the contact activation pathway, results in an abnormally prolonged aPTT test but a normal PT test.

* If S < sub > N </ sub > 1 and E1 pathways are competing, the E1 pathway can be favored by increasing the heat.

If disturbed, the pathway provides an obstacle-free escape route.

If the smaller population fragment becomes genetically isolated from the parental group, it may be subjected to its own unique mutations, selection forces, and genetic drift effects ; thus, it will follow its own evolutionary pathway.

If you do not gain direct entry into a degree at UC, you can choose from one of many pathway programs.

If bodies are prepared with separately uniform temperatures, and are then put into purely thermal communication with each other, by conductive or radiative pathways, they will be in thermal equilibrium with each other just when they have the same temperature, and then there will be no net transfer of heat between them ; but if initially they do not have the same temperature, heat will flow from the hotter to the colder, by whatever pathway, conductive or radiative, is available, and this flow will continue until thermal equilibrium is reached and then they will have the same temperature.

If conditions are acidic enough, the acetic acid can be further reacted via the Fischer esterification pathway, but at a much slower pace.

If the axons have myelin sheaths, then the pathway appears bright white because myelin is primarily lipid.

If most or all of the axons lack myelin sheaths ( i. e., are unmyelinated ), then the pathway will appear a darker beige color, which is generally called grey ( British English, or gray in American English ).

If you have your sights set on a specific career, an occupational program may be just the right pathway to help you achieve your career goals.

If there is atrial fibrillation with pre-excitation, treatment options include procainamide, flecainide, propafenone, dofetilide and ibutilide since these medications slow conduction in the accessory pathway causing the tachycardia and should be administered before considering electrical cardioversion.

If the foreign molecule is not a protein, then proteolyic digestion can not occur and the T-dependent pathway described above does not operate.

If the third order neuron ( the last of three neurons in the pathway which ultimately discharges norepinephrine into the synaptic cleft ) is intact, then the amphetamine causes neurotransmitter vesicle release, thus releasing norepinephrine into the synaptic cleft and resulting in robust mydriasis of the affected pupil.

If the organism does not contain the complete pathway for the desired product or result, then genes that produce the missing enzymes must be incorporated into the organism.

If there is a black region with only one possible way to connect to the rest of the board, the sole connecting pathway must be black.

If there is a white region that does not contain a number, and there is only one possible way for it to connect to a numbered white region, the sole connecting pathway must be white.

If this pathway is blocked, it leads to pericyte deficiency.

If any part of this pathway is damaged blindness can occur.

If both front and rear surfaces of the device meet this criterion, the light will be ' trapped ' by not having an immediate pathway out of the device due to internal reflections.

If a project does not require approval under Part 3A or Part 4 it is then potentially captured by the third pathway, Part 5 dealing with environment impact assessment.

If any of us miss, they can pick up the pieces.

`` If you can conveniently let me have twenty dollars '', he wrote one friend in 1791 when he was Secretary of the Treasury.

If we cannot stop warfare in our own economic system, how can we expect to abolish it internationally??

If our sincerity is granted, and it is granted, the discrepancy can only be explained by the fact that we have come to believe hearsay and legend about ourselves in preference to an understanding gained by earnest self-examination.

If Mrs. Wright doesn't accept the terms in the morning, I'll go either to Tokyo or to Holland, to do what I can.

If within one year you can make a success out of the American, you can practically name your own salary thereafter.

If it is not one of his best books, it can only be considered unsatisfactory when compared with his own Garibaldi.

If there be a disinterested patriot in America, 'tis General Washington, and his bravery, none can question ''.

`` If you can firmly make the good knight sure to pleasure our Corporation '', Sturley wrote, `` besides that ordinary allowance for your diet you shall have 20 for recompence ''.

If man is actually the product of his environment and if science can discover the laws of human nature and the ways in which environment determines what people do, then someone -- a someone probably standing outside traditional systems of values -- can turn around and develop completely efficient means for controlling people.

If the manner of his passing moves the nations to act in the spirit of his dedication the sore issues that plague the world can yet be resolved with reason and justice.

If they do as well as they did in 1960 there can be no complaint.

If he can bounce back with one of those 25 home runs years, the club will have to be better off offensively.

If it will simply delay the debates until the qualifications are closed next spring, and then carry all the candidates on a tour of debates, it can provide a service to the state.

`` If the day should ever come that foreign invaders swarm ashore along the Gulf Coast '', the account reads, `` they can count on heavy opposition from a group of commando-trained telephone employees -- all girls.

If we cluster together, the redcoats can make an advantage out of it, but there's not a blessed thing they can do with two or three of us except chase us, and we can outrun them ''.

If there is anything which we can do in the executive branch of the Government to speed up the processes by which we come to decisions on matters on which we must act promptly, that in itself would be a major contribution to the conduct of our affairs.

If the target can change its position significantly during the 30 minutes the missile is in the air on its way, the probability of the missile destroying the target is drastically reduced.

If your state has no provisions for the numbering of pleasure boats, you must apply for a number from the U.S. Coast Guard for any kind of boat with mechanical propulsion rated at more than 10 horsepower before it can be used on Federal waterways.

If there are any major restrictions, they usually can be obtained in printed form.

Note: If 1/2-inch panel board is used inside and out, or 5/8-inch one side and 3/8-inch the other, and 1/8-inch glass is used, stock lumber in Af, Af, and Af can be used in making the glass panels.