Before the actual process of cell death is precipitated by enzymes, apoptotic signals must cause regulatory proteins to initiate the apoptosis pathway.

Before the actual discovery of mendelevium, the trivalent state was the most stable one in aqueous solution.

Before the actual trial could be held, Clement persuaded Philip to leave the question of Boniface's guilt to the Council of Vienne, which met in 1311.

Before the 2010 regulations, the complete list of the actual and theoretical varieties also included Pinot de Juillet and Pinot Rosé.

Before starting the actual reading, the reader will typically try to elicit cooperation from the subject, saying something such as, " I often see images that are a bit unclear and which may sometimes mean more to you than to me ; if you help, we can together uncover new things about you.

Before actual work began, three main buildings were demolished: the palace of the Archbishop, the Ordinari Palace and the Baptistry of St. Stephen at the Spring, while the old church of Sta.

Before the English translation of Japanese name to Zeon was canonized by Nippon Sunrise in the late 1990s, it was sometimes translated as Zion or Jion, with the latter being closer to actual pronunciation in Japanese.

Before the market opens on the first day of trading a new futures contract, there is a specification but no actual contracts exist.

Before metrification at the FCC, the procedure to figure HAAT was relatively simple: from the proposed or actual antenna site, either 12 or 16 radials were drawn, and points at 2, 4, 6, 8, and radius along each radial were used.

Before the Romulans open fire, Peter challenges the Romulan commander to a ritual fight-to-the-death ( using an obscure but still valid Romulan law predating their schism with the Vulcans ), in which actual battle is prohibited until the contest is resolved.

Before it was known and recognized as the common colourful plastic toy ( sometimes with water inside the actual hoop ), it used to be made of dried up willow, rattan, grapevines, or stiff grasses.

Before then, it used the traditional regimental system, where regiments were actual combat units.

Before maturity, the actual value of a bond may be greater or less than face value, depending on the interest rate payable and the perceived risk of default.

Before actual construction of the building could begin, American Fletcher became the first major Indianapolis bank holding company to be sold to an out-of-state financial institution, agreeing in the spring of 1986 to merge with Ohio's rapidly growing Bank One Corporation.

Before its release, the game was met with derision from some due to Microsoft's marketing department Photoshopping lens flares onto what were supposedly actual game screenshots.

Before modern refrigeration was available, Iceboxes were popular, The problem with an icebox was that the cabinet housing it was large, but the actual refrigerated space was quite small.

Before long, his banter with the audience overtook the actual songs ; he became known more as a comedian than a singer.

Before the actual construction started, the terrain was evenly covered with sand from the Sava and the Danube rivers in an effort to dry out the land and raise it above the reach of flooding and underground streams.

Before studying the actual relocation of Aultsville and its populace, it is important to understand the development of the St. Lawrence Seaway Project first.

Before Habonim was named in spring 1929, Chaim ( actual name Hyman S .) Lipshitz as co-founder, had regular organized meetings of boys at his father's Cheder ( school room ) and they were well established by December 1928.

Before this point in time, the growth of the fireball was due to radiative transport, i. e. thermal x-rays " outpaced " the actual expanding bomb debris.

Before the British Invasions, writers in the American comic book industry were known as " ace storytellers but mediocre wordsmiths " because the " actual text " of their comic books were generally subordinate to the plot and storytelling.

Before Persil, laundry soaps consisted of either soap flakes or actual bars of soap.

Before a match, the player chooses three of the characters to use in the actual fights, while the fourth member becomes the designated " Striker ", a character the player summons during battle to help their character out by performing one of their Special Moves against the opponent.

Before he went into battle Andrei had told Alex, `` I only want to be a Pole.

As his ship was readied for battle, Nelson held a final dinner with Vanguard < nowiki >'</ nowiki > s officers, announcing as he rose: " Before this time tomorrow I shall have gained a peerage or Westminster Abbey ," in reference to the rewards of victory or the traditional burial place of British military heroes.

Before the battle, the Cossack army totaled 80, 000 men ; 28, 000-33, 000 Tatars and uncertain numbers of Ukrainian peasants.

Before the battle, one of Mark Antony's generals, Quintus Dellius, had defected to Octavian, bringing with him Mark Antony's battle plans.

Before sailing for home, Eleanor got the terrible news that Raymond, with whom she had the winning battle plan for the Crusade, had been beheaded by the overpowering forces of the Muslim armies from Edessa.

Before that battle, a series of omens had been witnessed, including a series of lightning bolts, which Fabius had believed were warnings from the gods.

Before a battle the sarissa were carried in two pieces and then slid together when they were being used.

Before Mormon's death in battle, he passed the golden plates to Moroni.

In the episode " Before and After ", Kes participates in Voyager's year-long battle with the Krenim, becoming infected with particles from a chronoton torpedo.

Before the battle, Oswald had a wooden cross erected ; he knelt down, holding the cross in position until enough earth had been thrown in the hole to make it stand firm.

Before the battle started, Muhammad had given orders for the Muslims to attack with their ranged weapons, and only engage the Quraysh with melee weapons when they advanced.

Before he died in battle, he was reported to have said: " Let it never be the case that a Bohemian king runs a fight!

Before father and son can be reconciled, George is killed at the battle of Waterloo, leaving the pregnant Amelia to carry on as well as she can.

Before the battle, Henry rallies his troops with the famous St. Crispin's Day Speech, referring to " we few, we happy few, we band of brothers ".

Sherman offered Grant an example from his own life, " Before the battle of Shiloh, I was cast down by a mere newspaper assertion of ' crazy ', but that single battle gave me new life, and I'm now in high feather.

Before Cyrus and his army crossed the Aras River to battle with northern tribes, he installed his son Cambyses II as king in case he should not return from battle.

" Before sending Admiral Wilhelm Marschall out in Operation Juno, Raeder told him: " We must engage the enemy in battle, even if this should cost us one of the battleships.

Before the battle began, an army of Orcs and Wargs descended on Erebor.

Before the battle, Abijah addressed the armies of Israel, urging them to submit and to let the Kingdom of Israel be whole again.

Before the battle King Charles II contracted the Worcester Clothiers to outfit his army with uniforms but was unable to pay the £ 453. 3s bill.

Before the Tripartite Dinner Meeting of November 29, 1943 at the Tehran Conference, Churchill presented Stalin with a specially commissioned ceremonial sword ( the " Sword of Stalingrad ", made in Sheffield ) commemorating the victory in the battle of Stalingrad, as a gift from King George VI to the citizens of Stalingrad and the people of the Soviet Union.

Before the battle, there was evidently much debate amongst the Boeotarchs about whether to fight or not.