These modifications are often essential for the function or regulation of a protein ; for example, the carboxylation of glutamate allows for better binding of calcium cations, and the hydroxylation of proline is critical for maintaining connective tissues.

These preaching friars, with the authorization of Gregory IX, adopted ( with some modifications, e. g. the substitution of the " Gallican " for the " Roman " version of the Psalter ) the Breviary hitherto used exclusively by the Roman court, and with it gradually swept out of Europe all the earlier partial books ( Legendaries, Responsories ), & c., and to some extent the local Breviaries, like that of Sarum.

These practices, which matured in the Tang Dynasty, were to be inherited by the later dynasties with some modifications.

These modifications may also form a signal sequence which determines the final destination of the protein.

These successes allowed the government to concentrate in 1996 and 1997 on major structural reforms such as the implementation of a fully funded pension system ( partly modelled after Chile's pension system with major modifications ), reform of higher education, and the creation of a national treasury.

These modifications of the basic 8086 design were one of the first jobs assigned to Intel's then new design office and laboratory in Haifa, Israel.

These factors also make it quite common for modern-day builders to promote modifications to the basic design, such as adding a finger board, pedal, electronic pickup, drum head, or making the staff immovable.

These modifications include acetylation, methylation, ubiquitylation, phosphorylation and sumoylation.

These tournaments increasingly made various modifications to the College Bowl format, and came to be known as quiz bowl.

These cars are closer to standard form than in GT2, and in most cases modifications are restricted to those found in one-make cups.

These modifications make it easier to enter and exit the movement, and thus easier to incorporate into a long sequence of calls.

These changes include histone modifications, such as histone H3 methylation and histone H2A ubiquitination, as well as direct modification of the DNA itself, via the methylation of CpG sites.

These modifications also increase the stiffness and torsional rigidity of the chassis and have been adopted in Locosts in other countries.

These data include artifacts ( objects made or modified by humans ), features ( modifications to the site itself such as post molds, burials, and hearths ), ecofacts ( evidence for the local environment and resources being used such as snail shells, seeds, and butchered bones ).

These cars were built in five series and several modifications until 1996.

These rules have gone through a lot of modifications over the years.

These modifications stayed into use until the disintegration of the USSR on 25 December 1991, at which time the flag ceased to be a national flag.

These vibrations can be controlled by adding features like close-fitting spring guides or by aftermarket tuning done by " air-gunsmiths " who specialize in air gun modifications.

These sports are typically played using International Federation of Association Football ( FIFA ) rules, with modifications to the field of play, equipment, numbers of players, and other rules as required to make the game suitable for the athletes.

These changes are largely due to highly controlled modifications in gene expression.

These modifications encode the source location, and may be captured via an impulse response which relates the source location and the ear location.

These modifications include the shape of the listener's outer ear, the shape of the listener's head and body, the acoustical characteristics of the space in which the sound is played, and so on.

These modifications make Safari on Mac OS X and Windows look more similar to Safari on iPhone than previous versions.

These PTIs provided useful data for subsequent engineering modifications.

These were the ones Keith sought out -- the loners, the ones who killed for the joy of it, like himself.

These were the last words he ever uttered.

These two were going to be easy pickins.

These performances were being staged at historical monuments throughout Europe.

These were Oneida Indians.

These conceptions and the manner in which they were transposed into poetry or engendered by poetic form are intrinsic to western life from the time of Aeschylus to that of Shakespeare.

These basic ideas concerning the nature of religion were, Adams believed, some of the major keys to the understanding of history and the movement of society.

These were his public academic activities, domi forisque, in the college and in the university.

These early experiments were evidently not altogether satisfying to Patchen.

These people were not talking much about it, but you, a foreigner, sensed their apprehension and disappointment.

These public efforts were rare because Mr. Rayburn normally did his counseling, persuading and educating long before an issue reached its test on the House floor.

These microfossils indicate the swamp was `` formed during the Lower Cretaceous period when dinosaurs were at their heyday and when the first flowering plants were just appearing.

These were heroes nine feet tall to him ''.

These little songs, however, were sweet nothings from the heart, tender memories of his childhood, little melodies that anyone could hum and that would make one want to weep.

These were the ships of His Majesty's Navy, herding the hulks of the East Indies merchants and the yachts and ketches of the loyalists.

These trumps were more touching than they were anything else, and seemed to imply that the nights were long, her children ungrateful, and her marriage bewilderingly threadbare.

These were selected carefully and included not only detailed clinical information but adequate pathology of value for research and educational purposes.

These amendments to the Vocational Rehabilitation Act were designed to help provide for more specialized rehabilitation facilities, for more sheltered and `` half-way '' workshops, for greater numbers of adequately trained personnel, for more comprehensive services to individuals ( particularly to the homebound and the blind ), and for other administrative improvements to increase the program's overall effectiveness.

These plans, like Du Pont's, contained provisions for passing the vote on Du Pont's General Motors shares on to the ultimate stockholders of Du Pont, Christiana, and Delaware, except that officers and directors of the three companies, their spouses, and other people living in their households, as well as other specified persons, were to be totally disenfranchised.

These curves were derived by an analysis of extensive skywave measurement data.

These were educated men, who, as Mr. Justice Holmes was fond of saying, formed their inductions out of experience under the burden of responsibility.

These boys acknowledged an introduction to anybody by gently pressing one of his hands in both of theirs, while they gazed, misty-eyed with care, into the eyes of the person they were meeting.