Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon entering Afghanistan, Soviet soldiers became immediately aware of the falsity of the reported situation.

Upon arrival in Afghanistan, ( Hicks was sent to Afghanistan by the LoT ) Hicks allegedly went to an al-Qaeda ( he did not know of the existence of al-Qaeda until he was interrogated by USA army personnel ) guest house where he met Ibn al-Shaykh al-Libi, a high ranking al Qaeda member.

Testimony at the National Commission on Terrorist Attacks Upon the United States ( ongoing during March 2004 ) has included claims of how much of the Bush administration's immediate post-9 / 11 emphasis on Iraq was appropriate and proportional to the overall picture of terrorism, especially in light of the administration's subsequent decision to pursue military action in Afghanistan first, the fact that organizations accused of 9 / 11 are in Afghanistan, not Iraq, and that no links have been found between these organizations and Saddam Hussein.

Upon Sultan Ghauri's death in 1206, Qutb, after a brief power struggle, succeeded in establishing himself as ruler of the kingdom in Afghanistan, and northern India ; Shahabuddin Muhammad's Central Asian possessions had been captured by none other than the Mongol warlord, Genghis Khan.

Upon arriving at school, the boys discover that they must, in response to President Bush's request for charity to Afghanistan, donate a dollar.

Upon arrival to Kandahar, Afghanistan, " First Strike " assumed a large battle space and immediately began conducting combat operations in Zhari District, an area known for years as a Taliban sanctuary.

Upon release, the film was criticized for not addressing many current issues of the New Left such as the woman's movement, sexual liberation and worker self-management.

Upon his return, he regained the lost ground resulted from the First Council of Nicaea, established alliances with other groups such as the Meletians and expelled many opponents.

Upon his arrival in London, Hayek was quickly recognized as one of the leading economic theorists in the world, and his development of the economics of processes in time and the coordination function of prices inspired the ground-breaking work of John Hicks, Abba Lerner, and many others in the development of modern microeconomics.

Upon many suggestions, the date of the Emperor's proclamation on January 18th would be established as day of remembrance.

Upon Henry ’ s death, the Norman and English barons ignored Matilda ’ s claim to the throne, and thus through a series of decisions, Stephen, Henry ’ s favourite nephew, was welcomed by many in England and Normandy as their new ruler.

Upon witnessing so many men going to their death on the brash whim of an impulsive prince, Hamlet declares, " O, from this time forth, / My thoughts be bloody, or be nothing worth!

Upon contact with prey, the contents of the nematocyst are explosively discharged, firing a dart-like thread containing neurotoxins into whatever triggered the release which can paralyse the prey, especially if many hundreds of nematocysts are fired.

Upon taking Mazar-i-Sharif in 1998, about 4, 000 civilians were executed by the Taliban and many more reported tortured.

" Upon taking Mazar-i-Sharif in 1998, about 4, 000-6, 000 civilians were killed in an ethnic cleansing campaign by the Taliban and many more reported tortured.

Upon the John Byrne reboot of the Superman mythos after Crisis on Infinite Earths, kryptonite was made much rarer in the DC Universe and many of the multicolored varieties were eliminated.

Upon achieving independence, Slovenia offered citizenship to all residents, regardless of ethnicity or origin, avoiding a sectarian trap that has caught out many central European countries.

Upon investigation, he concluded that because many different agencies and private parties had rights over the use of store space, it was difficult or even impossible for a startup retailer to negotiate successfully the use of that space.

Upon arriving at their destinations, many fugitives were disappointed.

Upon winning the election, Harding appointed many of his longtime allies and campaign contributors to prominent political positions in control of vast amounts of government money and resources.

Upon gaining power, Yusuf attacked the Aksumite garrison in Zafar, the Himyarite capital, killing many and destroying the church there.

Upon the completion of their work on the CPRR's portion of the Pacific Railroad, many Chinese workers moved on to other railroad construction jobs including with the Central Pacific.

Once Upon a Time in the West emerged as a long, violent, dreamlike meditation upon the mythology of the American Old West, with many stylistic references to iconic western films.

Upon the capture and plunder of Thessaloniki, many of its inhabitants escaped, including intellectuals such as Theodorus Gaza " Thessalonicensis " and Andronicus Callistus.

Upon release in August 1976 The Outlaw Josey Wales was widely acclaimed, with many critics and viewers seeing Eastwood's role as an iconic one that related to America's ancestral past and the destiny of the nation after the American Civil War.

Upon the death of his father in 1805, he joined the freethinking household of his mother at Auteuil, and spent two years mixing with the literary set of the so-called " ideologues ", philosophers of the 18th-century school, among whom he made many friends, notably Claude Charles Fauriel.

Upon becoming king in 1481, John II of Portugal set out on many long reforms.

Upon hearing of the death of Lentulus and the others, many men deserted his army, reducing the size from about 10, 000 to a mere 3, 000.

Upon learning of someone else's suicide, many people decide that action is appropriate for them as well, especially if the publicized suicide was of someone in a similar situation as them.

Upon hearing of the attacks, many mission priests ( along with a few government officials ) sought refuge at Mission Nuestra Señora de la Soledad, the mission chain's most isolated outpost.

Upon Théoden's restoration, " many things which men had missed " were found locked in Gríma's trunk, including the king's sword, Herugrim.