Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon the completion of the Jarrow Monastery, Ceolfrid became the Abbot of the St. Paul's Church on the monasterial grounds.

Upon hearing of the persecution of Copts because of the actions of the Crusaders ', he returned to St. Anthony's Monastery.

Upon Yekuno Amlak's ascension to the throne, Istifanos Church became Istifanos Monastery.

Upon his return to Russia ( between 1473 and 1489 ), Nil Sorsky founded a cloister on the Sora River ( hence, Nil Sorsky, or Nil of Sora ) not far from the Kirillo-Belozersky Monastery, where he would settle down with his followers.

Upon Dimitry's death on October 28, 1709 his relics were placed at St. Jacob's Monastery, which his followers would rebuild as Dimitry's shrine.

Upon his birth, he was recognized by the Sixteenth Gyalwang Karmapa as the seventh in the line of Dzogchen Ponlop incarnations and was formally enthroned as The Seventh Dzogchen Ponlop Rinpoche at Rumtek Monastery in 1968 .< ref >

Upon stepping onto the surface, Young expressed his sentiments about being there: " There you are: Mysterious and Unknown Descartes.

Upon arrival at the Central Station: " the first glance at the place was enough to let you see the flabby devil was running that show.

Upon being asked, " But Doctor Johnson, do you really believe that any man today could write such poetry?

Upon seeing the spirit of Samuel Saul fell with his face to the ground and Samuel asked Saul " Why have you disquieted me, to bring me up?

Upon leaving an Ashkenazic shiva house, visitors recite a traditional blessing: " May God comfort you among the other mourners of Zion and Jerusalem " ( המקום ינחם אתכם בתוך שאר אבלי ציון וירושלים, transliterated HaMakom yenachem etchem betoch sha ' ar aveylei Tziyon viYerushalayim ).

Upon being admitted to the prison he is quoted as saying, " I will be the meanest bastard you ever saw when I get out of here.

Upon accepting, Hoffman stated softly to his fellow nominees that it was okay if they didn't vote for him because " I didn't vote for you guys either.

Upon hearing of Mohandas Gandhi, he joked to Mavlankar that Gandhi would " ask you if you know how to sift pebbles from wheat.

Upon finding him, Muybridge said, " Good evening, Major, my name is Muybridge and here's the answer to the letter you sent my wife ", and shot him pointblank.

Upon entering Wabasha you will see a sign reading " Welcome to Wabasha, Home of Grumpy Old Men ".

Upon hearing this notion, a frenzied Curtis grabbed a spade and threw it over Confederate trenches and shouted, " Dig Johnnies, for I'm coming for you.

Upon David's first meeting with Shirley before co-starring with her on The Partridge Family, he said, " The day he tells me that they're divorced, he tells me, ' We're remarried, and let me introduce you to my new wife.

Upon their mastery of the strategy and timing listed in the five books, Musashi states that you will be able to defeat ten men as easily as you could defeat one, and asks: " When you have reached this point, will it not mean that you are invincible?

Upon the arrest, Hanssen realized his espionage days against the FBI were over, and said, " What took you so long?

" O Spirit, as a runner strips / Upon a windy afternoon / Be unencumbered of what troubles you --/ Arise with grace / And greatly go, with the wind upon your face.

Here, the entire congregation pauses for a moment of silent confession, recites the confiteor, and receives God's forgiveness through the pastor as he says the following ( or similar ): " Upon this your confession and in the stead and by the command of my Lord Jesus Christ, I forgive you all your sins in the name of the Father and of the Son and of the Holy Spirit.

" Upon hearing of this, scriptwriter Robert Bolt said to him " Well, if you just finish working on this wretched little film and then do yourself in, I'd be happy to stand the expenses of your burial.

Upon meeting Columbo dressed in the raincoat, the Captain of the ship quips " Oh, tell me Lieutenant, do you expect inclement weather in the Mexican waters?

Upon their return home their father asked them, " How is it that you have come back so soon today?

Upon his departure, Parcells famously stated: " They want you to cook the dinner ; at least they ought to let you shop for some of the groceries.