Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon taking office, Kabila called for multilateral peace talks to end the war.

Upon hearing of Polk's election to office, Tyler urged Congress to pass a joint resolution admitting Texas to the Union ; Congress complied on February 28, 1845.

Upon the conclusion of the 2010 season, the Mets front office fired General Manager Omar Minaya and Manager Jerry Manuel.

Upon confirmation, Tombaugh walked into Slipher's office and declared, " Doctor Slipher, I have found your Planet X.

Upon election, however, Robinson took steps to de-politicize the office.

Upon taking office, Milošević gained direct control of the Yugoslav military and security forces, and directed them to engage Kosovo separatists.

Upon becoming President of Egypt following the death in office of President Gamal Abdel Nasser, Anwar Al-Sadat sought a diplomatic solution to the conflict, offering peace and recognition to Israel in exchange for the Israeli withdrawal from all the Egyptian, Palestinian, and Syrian territory occupied in 1967, and a resolution of the Palestinian refugee problem.

Upon assuming office in 1981, U. S. President Ronald Reagan condemned the FSLN for joining with Cuba in supporting Marxist revolutionary movements in other Latin American countries such as El Salvador.

Upon Voldemaras ' removal from office, Geležinis Vilkas went underground and received aid and encouragement in its activities from Germany.

Upon release in May 1975 The Eiger Sanction was a commercial failure, receiving only $ 23. 8 million ( US $ in dollars ) at the box office, and was poorly received by most critics.

Upon taking office, Paul II was to convene an ecumenical council within three years.

Upon his defeat, Tilden said, " I can retire to public life with the consciousness that I shall receive from posterity the credit of having been elected to the highest position in the gift of the people, without any of the cares and responsibilities of the office.

Upon assuming office, Turner, who had been out of politics for nine years while he earned a lucrative salary as a Toronto lawyer, showed that his political instincts had diminished.

Upon further investigation of the man stalking him, Taylor found a dead body in an office of an unused floor in the building.

Upon the start of the new Stuart dynasty in 1603, Buck was knighted ( on 23 July ) and formally received the reversion to the office of Master of the Revels with an appointment as Deputy Master, by a royal patent ( on 23 June ).

' Upon seeing this, the young men of the town thought it to be rather an imposition, and collected together, procured the services of the band, and under the direction of a military officer marched to the rear of the hotel, and with a wheelbarrow and shovel took the empty keg that had been broken open, and playing the dead march with flag at half staff marched to the flagpole in front of Humiston ’ s office where they dug a grave and gave the empty keg a burial with all the honors attending a soldier ’ s funeral.

The film was originally to be released in summer 1977, but was pushed back to November because of the various problems during production, Upon its release, Close Encounters became a box office success, grossing $ 116. 39 million in North America and $ 171. 7 million in foreign countries, totaling $ 288 million.

Upon Mazarin's return, Fouquet demanded and received as reward the office of superintendent of the finances ( 1653 ), a position which, in the unsettled condition of the government, threw into his hands not merely the decision as to which funds should be applied to meet the demands of the state's creditors, but also the negotiations with the great financiers who lent money to the king.

Upon Congo's independence from Belgium, he was elected president by the Congo's new national assembly, taking office on June 30, 1960.

Upon graduation, he had no money to await appointment to academic office.

Upon leaving office, Banzer formed the ADN party ( Acción Democrática Nacionalista ), a large organization that attracted most conservative groups under his leadership.

Upon Robert's death, his ex-graduate student Hal discovers a paradigm-shifting proof about prime numbers in Robert's office.

Upon its release in March 1994, The Hudsucker Proxy received mixed reviews from critics, and was a box office bomb.