# A cytoplasmic C-terminal domain ( CTD ) consisting of a pair of RCK domains that assemble into an octameric gating ring on the intracellular side of the tetrameric channel.

# The deprotonated S195 serves as a nucleophile, attacking the carbonyl carbon on the C-terminal side of the residue and forcing the carbonyl oxygen to accept an electron, and transforming the sp2 carbon into a tetrahedral intermediate.

# HIV decreases the production of molecules involved in marking the cell for apoptosis, giving the virus time to replicate and continue releasing apoptotic agents and virions into the surrounding tissue.

# Very difficult to train: Bodhisattvas who attain this bhūmi strive to help sentient beings attain maturity, and do not become emotionally involved when such beings respond negatively, both of which are difficult to do.

# Take blood work to see if drugs were involved or if it was a result of hypoventilation / hyperventilation

* Wound healing # Overview of involved growth factors

# Humans are inevitably involved in production relations ( roughly speaking, economic relationships or institutions ), which constitute our most decisive social relations.

# If A is a disjoint union of countably many disjoint Lebesgue measurable sets, then A is itself Lebesgue measurable and λ ( A ) is equal to the sum ( or infinite series ) of the measures of the involved measurable sets.

# developing an analysis of risks involved in the process

# To excite the potential user about the product and instill in them a desire for becoming more involved with it.

# Some proteins involved in cell adhesion prevent tumor cells from dispersing, block loss of contact inhibition, and inhibit metastasis.

# The AAH can be explained simply and easily, lacking the myriad details and complicated theorizing involved in dealing with primary sources and materials.

# Exploitation-smuggling operations and interaction between smuggler and customer usually terminate upon payment and arrival at destination ; trafficking victims, on the other hand, are often involved in a cycle of ongoing exploitation.

# The development of a plan for evangelism that involved further organization, including the establishment of Sunday Schools and Bible classes ; and the ordination of selected believers as ministers.

# liability to become involved in intense and unstable relationships, often leading to emotional crisis ;

Under different circumstances, this could have been a very significant match beyond the star power involved, but since the International Team ( Norman ) won by a lopsided margin over the U. S. Team ( Woods ), this match had little effect on the final result, though it was a riveting match between the former and current # 1 players in the world.

He was involved in the printing of an edition of Tyndale's New Testament in 1535 ( Herbert # 15 ).

1, # 2 ( May 1947 ); it involved dope-dealing protagonist Mary Kennedy nearly getting stabbed in the eye " by a junkie with a hypothermic needle " in her dream sequence ).

# The extreme logistical challenges involved in successfully exchanging the money for the return of the victim without being apprehended or surveiled.

Prior to her marriage to Stewart, Fahey was romantically involved with Jim Reilly, the drummer for the Northern Irish punk rock band Stiff Little Fingers and Scottish singer Bobby Bluebell of The Bluebells, with whom she co-wrote the UK # 1 pop song " Young At Heart ".

# The Mediums ' Book — Details the mechanics of the spiritual world, the processes involved in channeling spirits, techniques to be developed by mediums, etc.

# Analyst: Handles the details involved in executing the project.

# Another Fine Mess .....: When responding to a distress call from a ship under attack by pirates, the Enterprise discovers none other than Harry Mudd is involved.

# The defendant must have become involved in the situation through no fault of his or her own

# a person involved in, and with, abstract, erudite ideas and theories ;

Typically the resulting steam is mixed into the gas flow and may be involved with subsequent chemical reactions, notably the water-gas reaction if the temperature is sufficiently high enough ( see step # 5 ).

# The nuclear envelope becomes discontinuous and the DNA inside it is fragmented in a process referred to as karyorrhexis.

# DNA wraps around histone proteins forming nucleosomes ; the " beads on a string " structure ( euchromatin ).

# Higher-level DNA packaging of the 30 nm fibre into the metaphase chromosome ( during mitosis and meiosis ).

# Simple and concise definition: Chromatin is DNA plus the proteins ( and RNA ) that package DNA within the cell nucleus.

# A biochemists ’ operational definition: Chromatin is the DNA / protein / RNA complex extracted from eukaryotic lysed interphase nuclei.

# The DNA + histone

# A eukaryotic cell transcribes the DNA ( from genes ) into RNA ( pre-mRNA ).

# A poly-T oligonucleotide primer is hybridized onto the poly-A tail of the mature mRNA template, or random hexamer primers can be added which contain every possible 6 base single strand of DNA and can therefore hybridize anywhere on the RNA ( Reverse transcriptase requires this double-stranded segment as a primer to start its operation.

# To synthesize an additional DNA strand, you need to digest the RNA of the hybrid strand, using an enzyme like RNase H.

# After digestion of the RNA, a single stranded DNA ( ssDNA ) is left and because single stranded nucleic acids are hydrophobic, it tends to loop around itself.

# From the hairpin loop, a DNA polymerase can then use it as a primer to transcribe a complementary sequence for the ss cDNA.

# REDIRECT DNA

# REDIRECT DNA microarray

# The DNA passes through a separate sugar transport protein ( ptsG ) in the inner membrane, and immediately circularises using the cos sites, 12-base G-C rich cohesive " sticky ends ".

# Host DNA gyrase puts negative supercoils in the circular chromosome, causing A-T rich regions to unwind and drive transcription.

# The host cell, containing a dormant phage genome, experiences DNA damage due to a high stress environment, and starts to undergo the SOS response.

# RecA ( a cellular protein ) detects DNA damage and becomes activated.

# Normally RecA * binds LexA ( a transcription repressor ), activating LexA auto-protease activity, which destroys LexA repressor allowing production of DNA repair proteins.

# Cleaved cI can no longer dimerise, and loses its affinity for DNA binding.

# The phage genome is still inserted in the host genome and needs excision for DNA replication to occur.

# Complementary DNA then binds to the U5 ( non-coding region ) and R region ( a direct repeat found at both ends of the RNA molecule ) of the viral RNA

# The primer then ‘ jumps ’ to the 3 ’ end of the viral genome and the newly synthesised DNA strands hybridizes to the complementary R region on the RNA

# The first strand of complementary DNA ( cDNA ) is extended and the majority of viral RNA is degraded by RNAse H