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Page "Chromatin" ¶ 4
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# and DNA
# The nuclear envelope becomes discontinuous and the DNA inside it is fragmented in a process referred to as karyorrhexis.
# Higher-level DNA packaging of the 30 nm fibre into the metaphase chromosome ( during mitosis and meiosis ).
# Simple and concise definition: Chromatin is DNA plus the proteins ( and RNA ) that package DNA within the cell nucleus.
# A biochemists ’ operational definition: Chromatin is the DNA / protein / RNA complex extracted from eukaryotic lysed interphase nuclei.
# The DNA + histone
# A eukaryotic cell transcribes the DNA ( from genes ) into RNA ( pre-mRNA ).
# A poly-T oligonucleotide primer is hybridized onto the poly-A tail of the mature mRNA template, or random hexamer primers can be added which contain every possible 6 base single strand of DNA and can therefore hybridize anywhere on the RNA ( Reverse transcriptase requires this double-stranded segment as a primer to start its operation.
# To synthesize an additional DNA strand, you need to digest the RNA of the hybrid strand, using an enzyme like RNase H.
# After digestion of the RNA, a single stranded DNA ( ssDNA ) is left and because single stranded nucleic acids are hydrophobic, it tends to loop around itself.
# From the hairpin loop, a DNA polymerase can then use it as a primer to transcribe a complementary sequence for the ss cDNA.
# REDIRECT DNA
# REDIRECT DNA microarray
# The DNA passes through a separate sugar transport protein ( ptsG ) in the inner membrane, and immediately circularises using the cos sites, 12-base G-C rich cohesive " sticky ends ".
# Host DNA gyrase puts negative supercoils in the circular chromosome, causing A-T rich regions to unwind and drive transcription.
# The host cell, containing a dormant phage genome, experiences DNA damage due to a high stress environment, and starts to undergo the SOS response.
# RecA ( a cellular protein ) detects DNA damage and becomes activated.
# Normally RecA * binds LexA ( a transcription repressor ), activating LexA auto-protease activity, which destroys LexA repressor allowing production of DNA repair proteins.
# Cleaved cI can no longer dimerise, and loses its affinity for DNA binding.
# The phage genome is still inserted in the host genome and needs excision for DNA replication to occur.
# C-terminal involved in downregulation of DNA binding of the central domain: residues 356-393.
# Complementary DNA then binds to the U5 ( non-coding region ) and R region ( a direct repeat found at both ends of the RNA molecule ) of the viral RNA
# The primer then ‘ jumps ’ to the 3 ’ end of the viral genome and the newly synthesised DNA strands hybridizes to the complementary R region on the RNA
# The first strand of complementary DNA ( cDNA ) is extended and the majority of viral RNA is degraded by RNAse H

# and wraps
# gate keeping bias, i. e., deciding whether to release a story or keep it under wraps ( see Spike ( journalism ))
# Volvent: a lasso-like string that is fired at prey and wraps around a cellular projection on the prey, referred to as spirocysts
# Complete with a half-hitch outside the loop, made in the same direction as the first two wraps, as for a clove hitch.
# Complete with a half-hitch outside the loop, made in the same direction as the first two wraps, as for a clove hitch.
# Complete with a half-hitch outside the loop made in the opposite direction than the first two wraps, as for a cow hitch.
In Fantastic Four # 43, she attacks Medusa with a series of force spheres, but then Medusa counters and wraps her up in her mighty hair.
# Mystery Solved: 2007 International Mystery Writers ' Festival wraps with top award going to Kentucky author ; accessed Jan 31, 2010

# and around
# Sleeping Murder ( written around 1940, published 1976 )
# 1. around 1200: Gertrude of Merania ( 1185 – 8 September 1213 ), a daughter of Berthold IV, Duke of Merania and his wife, Agnes of Wettin
# Bank doesn't have enough shares to allow everyone to trade in their shares-first choice falls to person causing the merger, followed by other players in order around the table in the order of play.
# Rapid speciation: presence of one or more bursts in the emergence of new species around the time that ecological and phenotypic divergence is underway.
# Another incorrect theory was that the heat on the dark side was causing the material to outgas, which pushed the radiometer around.
# The object moves with constant angular velocity around the circle.
# An electric current in a wire creates a circular magnetic field around the wire, its direction ( clockwise or counter-clockwise ) depending on that of the current.
# the Scattered Islands (), a dispersed group of islands around the coast of Madagascar.
# The final harmony that presently exists in the New Testament canon, around 85-90 AD.
# Shooting himself in the forehead: As his mother reads the questionnaire for the dating service ( and answers it according to her preferences, not his ), Harold surreptitiously loads a revolver with live rounds, then wheels around and points it at his mother.
# Arguments were drawn from the miraculous Acheiropoieta, the supposed icon of the Virgin painted with her approval by St Luke, and other miraculous occurrences around icons, that demonstrated divine approval of Iconodule practices.
His 1976 single " Hot ( I Need To Be Loved, Loved, Loved, Loved )" ( R & B # 31 ) used the main riff from " Fame " by David Bowie, not the other way around as was often believed.
# The ring current field, carried by plasma trapped in the dipole-like field around Earth, typically at distances 3 – 8 R < SUB > E </ SUB > ( less during large storms ).
# They could have been captured from around smaller passing stars.
# Koca Eli peninsular area around Izmit ;
# former principality of Karesi around Balikesir and Bergama.
# The orbit of a planet around the Sun is an ellipse, with the Sun in one of the focal points of the ellipse.
# As the planet moves around its orbit during a fixed amount of time, the line from the Sun to planet sweeps a constant area of the orbital plane, regardless of which part of its orbit the planet traces during that period of time.
# Saaremaa 3-day running marathon takes place on the roads around Kuressaare town and Sõrve peninsula.
# Richard was born before 1056, died around 1075.
# Matilda was born around 1061, died perhaps about 1086.
It is possible to describe the other Geocentrism | planets in the Solar System as revolving around the Earth, but that explanation is unnecessarily complex compared to the contemporary consensus that all planets in the Solar System Heliocentrism # The view of modern science | revolve around the Sun.

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