Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering the town of Blairsville, Georgia, one can see a plaque crediting John Thomas ( former Justice of the Inferior Court and serving Union County in the Georgia House of Representatives in 1833 ) for giving the county the name of Union.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon realizing the doll has vanished, Shelton suspects it stolen and forces all the cadets to do exercises in the courtyard as punishment.

Upon arrival at the camp, new inmates were brought to courtyard where they would have to stand facing the wall until they were processed into the camp.

Upon entering a dar, guests move through a zigzagging passageway that hides the central courtyard.

Upon entering the courtyard, one can see two antique buildings on both sides and two more on the foreground.

Upon arrival in Stettin after two months at sea, the materials were transferred onto a barge for the last leg of the journey to Berlin, where they were stored during the winter in the courtyard of the Altes Museum.

Upon contact with their ligand, TNF receptors also form trimers, their tips fitting into the grooves formed between TNF monomers.

Upon antigen binding, they cluster in large patches, which can exceed 1 micrometer in diameter, on lipid rafts that isolate the BCRs from most other cell signaling receptors.

Upon contact with prey, the contents of the nematocyst are explosively discharged, firing a dart-like thread containing neurotoxins into whatever triggered the release which can paralyse the prey, especially if many hundreds of nematocysts are fired.

Upon gaining 75 % pass marks, they can proceed to the next level.

Upon completion of this experiment, Loewi asserted that sympathetic regulation of cardiac function can be mediated through changes in chemical concentrations.

Upon visiting the site, visitors can create a free account.

Upon successful review by the members of the WGPSN, names are considered provisionally approved and can be used on maps and in publications as long as the provisional status is clearly stated.

Upon completing each episode, the player is returned to the hub Start level, where another episode can be entered.

Upon finally reuniting, this asymmetry can be seen in the actual difference showing on the two reunited clocks.

Upon learning that the Champion can return the Power Gem that contains the " Power Primordial " to himself at anytime, Titania smashed him with a giant rock mass, believing that he would be kept buried below it.

Upon leaving the house ( where it had been a cold, snowy night ), she enters a sunny spring garden where the flowers have the power of human speech ; they perceive Alice as being a " flower that can move about.

Upon further heating, they gradually soften, which can be characterized by certain softening points.

Upon the preference of the host, maps can be played with or without aliens.

Upon learning of Diệm's ouster and assassination, Hồ Chí Minh reportedly stated: “ I can scarcely believe the Americans would be so stupid .” The North Vietnamese Politburo was more explicit :“ The consequences of the 1 November coup d ' état will be contrary to the calculations of the U. S. imperialists ... Diệm was one of the strongest individuals resisting the people and Communism.

Upon drive failure, any subsequent reads can be calculated from the distributed parity such that the drive failure is masked from the end user.

* Senior Members: Upon meeting certain requirements, a professional member can apply for Senior Membership, which is the highest level of recognition that a professional member can directly apply for.

Upon his defeat, Tilden said, " I can retire to public life with the consciousness that I shall receive from posterity the credit of having been elected to the highest position in the gift of the people, without any of the cares and responsibilities of the office.

Upon receiving the news, John and Gisbourne plot to dispose of Richard quietly before he can raise an army.

Upon pressing the chestnut, a slight ' give ' can be felt ; the hull is not so tense, and there is space between it and the flesh of the fruit.

Upon passage of the new GI Bill President George W. Bush stated " Our nation has no greater responsibility than to support our men and women in uniform-especially because we're at war ," ... " This bill shows the American people that even in an election year, Republicans and Democrats can come together to support our troops and their families ," which highlighted that the new GI Bill had been overwhelmingly supported by both parties in the U. S. Congress.

Upon finishing their required courses, students can select from curricula of different tracks ( enterprise management, finance and banking, enterprise innovation and management, accounting analysis and management control, e-commerce, international business administration, etc .).

Upon showdown, each player makes the best five-card poker hand he can out of the seven cards he was dealt.

Upon joining a gang, they instantly gain a feeling of belonging and identity ; they are surrounded with individuals whom they can relate to.