Ligands may also bind elsewhere, however, as is the case for bulkier ligands ( e. g., proteins or large peptides ), which instead interact with the extracellular loops, or, as illustrated by the class C metabotropic glutamate receptors ( mGluRs ), the N-terminal tail.

* Ligands for interaction with lipoprotein receptors in tissues ( apoB100 and apoE for LDL-receptors, apoA-I for HDL receptors )

* Synthesis and Activity of Dafachronic Acid Ligands for the C. elegans DAF-12 Nuclear Hormone Receptor

Ligands that span the faces or edges of the M6 core are labeled L < sub > i </ sub >, for innen, and those ligands attached only to one metal are labeled L < sub > a </ sub >, for ausser.

Ligands are generally bound to the central atom by a coordinate covalent bond ( donating electrons from a lone electron pair into an empty metal orbital ), and are said to be coordinated to the atom.

Ligands that activate the non-canonical pathways are Wnt4, Wnt5a, and Wnt11.

Ligands can either have non-cooperativity, positive cooperativity or negative cooperativity.

Ligands bind to receptors and dissociate from them according to the law of mass action.

Ligands may interact with DNA by covalently binding, electrostatically binding, or intercalating.

The best-characterized ligand for the three selectins is P-selectin glycoprotein ligand-1 ( PSGL-1 ), which is a mucin-type glycoprotein expressed on all white blood cells.

These parts of the selectin molecules are responsible for their targeting to different compartments: P-selectin to secretory granules, E-selectin to the plasma membrane, and L-selectin to the tips of microfolds on leukocytes.

The best-characterized ligand for the three selectins is P-selectin glycoprotein ligand-1 ( PSGL-1 ), which is a mucin-type glycoprotein expressed on all white blood cells.

There's bound to be someone on guard, but the hat might fool them long enough for me to get close ''.

More of an agricultural nation, they have relied on their warriors only for defense and for survival in the endless wars of the plains.

They could hear the pony's feet on the dry leaves for a while, then the sound faded out.

For although I had crossed a corner of the hall on my way to the toilet I still could not tell for sure how far to the rear the darkness extended.

`` Soon as we send them on their way and make camp, let's you and me go for a walk down by the Snake -- all by ourselves ''.

Dan could hear Clayton Burnside and Eben Jackson summing up their final reckoning for rental on the oxen.

Rod shifted his eager eyes from the milling group out in the circle long enough to reply, `` I ain't much of a hand for Dare-Base and Farmer-in-the-Dell, but I'd sure like to get in on the handhold and wrestles ''.

He tramped out of the Miners Rest with his hopes plummeting, and headed doggedly for the Palace Saloon, the last place of any consequence on this side of the street.

Small rooms, probably for cards, opened off on either side.

Greg himself took two flights, with Todman leading the second, to patrol and look for targets of opportunities around Ormoc on the east coast of Leyte.

His face was dark as the sky above it as he stood on the wing and waited for his pilot.

He wondered where the superstition had originated that it was bad luck for a crew chief to watch his plane take off on a combat mission.

They were headed straight for each other on a collision course.

His burst held for a second on the engine section of the plane.

I started looking on the splintery truck bed for a piece of board, a dirt clod -- anything I could throw and with better aim than I had thrown the beer bottle.

She'd driven around for a while, Joyce said, then, thinking Louis Thor would have calmed down by that time, she'd gone back to his home on Bryn Mawr Drive, parked in front, and walked toward the pool.

`` They were supposed to meet Thor at nine PM for a conference concerning the ad campaign for their soap, a new angle based on this SX-21 stuff ''.

If it were not for an old professor who made me read the classics I would have been stymied on what to do, and now I understand why they are classics ; ;

I dismissed these feelings as wishful thinking but I could not get it out of my head that we had a strong physical attraction for one another and we both feared to dwell on it because of our relationship.

When we opened the door again for business and switched on the lights she said:

Packing a small suitcase, informing her husband whom she found in Harry's Bar that she was taking a train to Germany to get away for a while, patting his arm, refusing a drink, getting on the train -- all this had only taken her two hours.

But with her hand softly on his cheek for a last moment, she closed the door and he went back down the hall and into his bed excited, expectant, and finally faintly grinning with the feel of her hand against his mouth.

She set the dipper on the edge of the deck, leaving it for him to stretch after it while she looked on scornfully.

For example, in the presence of H < sub > 2 </ sub > O < sub > 2 </ sub > formed by the eosinophil, and either chloride or bromide ions, eosinophil peroxidase provides a potent mechanism by which eosinophils kill multicellular parasites ( such as, for example, the nematode worms involved in filariasis ); and also certain bacteria ( such as tuberculosis bacteria ).

The presence of eosinophils in the mucous lining of the nose and paranasal sinuses has been demonstrated for many patients, and this has been termed Eosinophilic Mucin RhinoSinusitis ( EMRS ).

Eosinophil granulocytes, usually called eosinophils or eosinophiles ( or, less commonly, acidophils ), are white blood cells that are one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates.

Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.

At these infectious sites, eosinophils are activated by Type 2 cytokines released from a specific subset of helper T cells ( T < sub > h </ sub > 2 ); IL-5, GM-CSF, and IL-3 are important for eosinophil activation as well as maturation.

The hypereosinophilic syndrome ( HES ) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils / mm³ ) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.

The American College of Rheumatology 1990 criteria for diagnosis of Churg-Strauss Syndrome lists the following criteria: asthma, blood eosinophilia > 10 %, presence of mononeuropathy or polyneuropathy, non-fixed pulmonary infiltrates, presence of paranasal sinus abnormalities, and histological evidence of extravascular eosinophils.