Ligands are generally bound to the central atom by a coordinate covalent bond ( donating electrons from a lone electron pair into an empty metal orbital ), and are said to be coordinated to the atom.

Ligands that activate the non-canonical pathways are Wnt4, Wnt5a, and Wnt11.

Ligands for P-selectin on eosinophils and neutrophils are similar sialylated, protease-sensitive, endo-beta-galactosidase-resistant structures, clearly different than those reported for E-selectin, and suggest disparate roles for P-selectin and E-selectin during recruitment during inflammatory responses.

* GABA < sub > B </ sub > Receptor Ligands

Ligands may also bind elsewhere, however, as is the case for bulkier ligands ( e. g., proteins or large peptides ), which instead interact with the extracellular loops, or, as illustrated by the class C metabotropic glutamate receptors ( mGluRs ), the N-terminal tail.

* Ligands for interaction with lipoprotein receptors in tissues ( apoB100 and apoE for LDL-receptors, apoA-I for HDL receptors )

* Synthesis and Activity of Dafachronic Acid Ligands for the C. elegans DAF-12 Nuclear Hormone Receptor

Ligands can either have non-cooperativity, positive cooperativity or negative cooperativity.

Ligands bind to receptors and dissociate from them according to the law of mass action.

Ligands may interact with DNA by covalently binding, electrostatically binding, or intercalating.

A defining touch found consistently across the long span of Francesco Zuccarelli's career is a serene and vaguely sweet expression on the rounded faces of his figures.

Infants scarcely a span long, with their faces cloven with hatchets and their bodies ghastly with wounds.

; < span id =" aspect "> Aspect </ span >: The direction in which a slope faces.

; < span id =" dihedral "> Dihedral </ span >: An inside corner of rock, with more than a 90-degree angle between the faces.

The walls are built up to the desired height layer-by-layer ( course by course ), and at intervals, large tie-stones or through stones are placed which span both faces of the wall.

Infants scarcely a span along, with their faces cloven with hatchets and their bodies ghastly with wounds.

; < span id =" face_climbing "> Face climbing </ span >: To ascend a vertical rock face using finger holds, edges and smears, i. e. not crack climbing.

; < span id =" friction "> Friction </ span >: Climbing technique relying on the friction between the sloped rock and the sole of the shoe to support the climber's weight, as opposed using holds or edges, cracks, etc.

A close relative, the Antarctic toothfish (< span lang =" la-Latn " style =" font-style: italic ;"> Dissostichus mawsoni </ span >), is found farther south around the edges of the Antarctic shelf ; and an MSC certified fishery is active in the Ross Sea.

Two solar panel wings, each 739 mm wide by 1537 mm long, extended from opposite edges of the base with a full span of 4. 6 m, and a pointable high gain dish antenna was hinge mounted at one of the corners of the base away from the solar panels.

Two solar panel wings, each 739 mm wide by 1537 mm long, extended from opposite edges of the base with a full span of 4. 6 m, and a pointable high gain dish antenna was hinge mounted at one of the corners of the base away from the solar panels.

Two solar panel wings, each 739 mm wide by 1537 mm long, extended from opposite edges of the base with a full span of 4. 6 m, and a pointable high gain dish antenna was hinge mounted at one of the corners of the base away from the solar panels.

The Bow River as well as the Fish Creek pass through the park, which used to span the width of the city but because of growth the city has surpassed the edges of the park.

* The splayed edges of the uppercase "< span style =' font-family: " Trebuchet MS ", sans-serif '> M </ span >" which form a 10 ° angle with a vertical line,

The core of the book is in the form of Belgarath's memoirs starting with his becoming an outcast from his village and becoming first disciple of the god Aldur and ending with the birth of Belgarion — a span of about seven thousand years.

There are three types of rotor: squirrel cage rotors made up of skewed ( to reduce noise ) bars of copper or aluminum that span the length of the rotor, slip ring rotors with windings connected to slip rings replacing the bars of the squirrel cage, and solid core rotors made from mild steel.

The group's core activities span Charity, Medicine, Education and Humanistic Culture, and it provides aid to all people regardless of race, religion or nationality.

; < span id =" bachar_ladder "> Bachar ladder </ span >: A piece of training equipment used to improve campusing and core strength.

While the core research is grounded in computer science, the applications studied span a large range of fields including military applications, ecology, seismology, security monitoring, and farming applications to name just a few.

The High Assurance Platform from NSA as implemented in General Dynamics ' Trusted Virtualization Environment ( TVE ) is another example-it uses SE Linux at its core, and can support MLS applications that span multiple domains.

CEB ’ s areas of service span the core functions found in large corporate, midsized, and government organizations, including:

C ° ntinuum states that the core question of the game is " If you could learn to span time at will.

The rapid rotation extends the life span of the star by increasing the core density and reducing the radiation output.

* David Wingrove's Chung Kuo series depicts a dystopian future Earth in which almost the entire population lives within several hyperstructures that are thousands of feet tall and span entire continents.

Triple bonds are highlighted < span style =" color: blue ;"> blue </ span >.

) acceptance tests may span multiple stories ( that are not implemented in the same sprint ) and there are different ways to test them out during actual sprints.

In a suspension or cable-stayed span, the elements in tension are distinct in shape and placement.

Beam bridges are horizontal beams supported at each end by substructure units and can be either simply supported when the beams only connect across a single span, or continuous when the beams are connected across two or more spans.

In one common challenge students are divided into groups and given a quantity of wood sticks, a distance to span, and glue, and then asked to construct a bridge that will be tested to destruction by the progressive addition of load at the center of the span.

About a third of all reports of Bigfoot sightings are concentrated in the Pacific Northwest, with most of the remaining reports spread throughout the rest of North America .< ref name =" Car08_p118 ">< span id =" Car08 "></ span ></ ref > Some Bigfoot advocates, such as John Willison Green, have postulated that Bigfoot is a worldwide phenomenon.

Many people with hypomania are actually in fact more productive than usual, while manic individuals have difficulty completing tasks due to a shortened attention span.

The archaeological remains are located in the north part of Björkö and span an area of about 7 hectares ( 17 acres ).

The researchers estimate there are up to 2, 000 coyotes living in " the greater Chicago area " and that this circumstance may well apply to many other urban landscapes in North America .< ref name =" urb ">< span class =" plainlinks ">" Thriving under our noses, stealthily: coyotes " URL accessed on January 9, 2006 .</ span ></ ref > In Washington, D. C .' s Rock Creek Park, coyotes den and raise their young, scavenge roadkill, and hunt rodents.

They can have a life span of 8 – 10 years in the wild, but live less than four years on average, as they are " a favourite food of jaguar, puma, ocelot, eagle and caiman ".

The remaining discs, which span five DVDs or over thirty CDs, contain all packages currently available and are not necessary for a standard install.

These expressions for the obliquity are intended for high precision over a relatively short time span, perhaps several centuries.

A calendar era indicates a span of many years which are numbered beginning at a specific reference date ( epoch ), which often marks the origin of a political state or cosmology, dynasty, ruler, the birth of a leader, or another significant historical or mythological event ; it is generally called after its focus accordingly as in Victorian era.

These birds are believed to have had a life span of about 20 to 25 years.

G proteins located within the cell are activated by G protein-coupled receptors ( GPCRs ) that span the cell membrane.

Continental motions due to plate tectonics are less than a kilometre over a span of only 10, 000 years.

His dates of birth and death are based on a life span of 60 years, the age at which Diogenes says he died, with the floruit in the middle.

Individual articles are read in portions proportional to the attention span, which depends on the user, his mood, the article, etc.