Ligands may also bind elsewhere, however, as is the case for bulkier ligands ( e. g., proteins or large peptides ), which instead interact with the extracellular loops, or, as illustrated by the class C metabotropic glutamate receptors ( mGluRs ), the N-terminal tail.

* Ligands for interaction with lipoprotein receptors in tissues ( apoB100 and apoE for LDL-receptors, apoA-I for HDL receptors )

" Colloidal Nanocrystals with Molecular Metal Chalcogenide Surface Ligands ".

Ligands are generally bound to the central atom by a coordinate covalent bond ( donating electrons from a lone electron pair into an empty metal orbital ), and are said to be coordinated to the atom.

* Systematic Evolution of Ligands by Exponential Enrichment, a molecular biology technique used in drug development

Ligands can either have non-cooperativity, positive cooperativity or negative cooperativity.

Ligands bind to receptors and dissociate from them according to the law of mass action.

Ligands that activate the non-canonical pathways are Wnt4, Wnt5a, and Wnt11.

* Synthesis and Activity of Dafachronic Acid Ligands for the C. elegans DAF-12 Nuclear Hormone Receptor

Ligands that span the faces or edges of the M6 core are labeled L < sub > i </ sub >, for innen, and those ligands attached only to one metal are labeled L < sub > a </ sub >, for ausser.

Ligands for P-selectin on eosinophils and neutrophils are similar sialylated, protease-sensitive, endo-beta-galactosidase-resistant structures, clearly different than those reported for E-selectin, and suggest disparate roles for P-selectin and E-selectin during recruitment during inflammatory responses.

Research indicates these drugs may interact with transcription factors known as " clock genes ", which may play a role in the addictive properties of drugs ( drug abuse ), and possibly in obesity.

The effects may differ for typical versus atypical antipsychotics and may interact with different stages of disorders.

Evidence suggests that environmental factors play a significant role in the development and course of bipolar disorder, and that individual psychosocial variables may interact with genetic dispositions.

But other thinkers sympathetic to his basic argument have suggested that the necessary ( though perhaps still not sufficient ) extra conditions may include the ability to pass not just the verbal version of the Turing test, but the robotic version, which requires grounding the robot's words in the robot's sensorimotor capacity to categorize and interact with the things in the world that its words are about, Turing-indistinguishably from a real person.

Contrary to brownian motion, which is the diffusion of a single particle, interactions between particles may have to be considered, unless the particles form an ideal mix with their solvent ( ideal mix conditions correspond to the case where the interactions between the solvent and particles are identical to the interactions between particles and the interactions between solvent molecules ; in this case, the particles do not interact when inside the solvent ).

For example, in optics two or more coherent lightwaves may interact and by constructive or destructive interference yield a resultant irradiance deviating from the sum of the component irradiances of the individual lightwaves.

It may interact with monoamine oxidase inhibitors, as well as other drugs that cause drowsiness.

Attributes are the elements responsible for storing information in a directory, and the schema defines the rules for which attributes may be used in an entry, the kinds of values that those attributes may have, and how clients may interact with those values.

The magnetospheres of the outer gas planets may weakly interact, although their magnetospheres are much smaller than Jupiter's.

Objects in each universe are essentially confined to the D-brane of their universe, but may be able to interact with other universes via gravity, a force which is not restricted to D-branes.

The existence of a neutrino mass strongly suggests the existence of a tiny neutrino magnetic moment of the order of, allowing the possibility that neutrinos may interact electromagnetically as well.

NSAIDs, like all drugs, may interact with other medications.

These free neutrons will then interact with the surrounding medium, and if more fissile fuel is present, some may be absorbed and cause more fissions.

If there is sufficient energy exchange between neighbouring dipoles they will interact, and may spontaneously align or anti-align and form magnetic domains, resulting in ferromagnetism ( permanent magnets ) or antiferromagnetism, respectively.

PLCs may need to interact with people for the purpose of configuration, alarm reporting or everyday control.

A simple system may use buttons and lights to interact with the user.

According to the rules of quantum field theory, and the associated Feynman diagrams, the above theory gives rise to three basic interactions: a quark may emit ( or absorb ) a gluon, a gluon may emit ( or absorb ) a gluon, and two gluons may directly interact.

The concept of religious pluralism is also relevant to human service professions, such as psychology and social work, as well as medicine and nursing, in which trained professionals may interact with clients from diverse faith traditions.

We may take her with us -- to California.

-- liberal considers that the need for a national economy with controls that will assure his conception of social justice is so great that individual and local liberties as well as democratic processes may have to yield before it.

Among Bourbons the racial issue may have less to do with their remaining unreconstructed than other factors.

Thus, to cite but one example, the Pax Britannica of the nineteenth century, whether with the British navy ruling the seas or with the City of London ruling world finance, was strictly national in motivation, however much other nations ( e.g., the United States ) may have incidentally benefited.

Yet he presents a realm of source material which may well serve other writers if not himself: the problems with which a New South must grapple in groping through a blind adolescence into the maturity of urbanization.

We are worried about what people may do with them -- that some crazy fool may `` push the button ''.

I am usually filled with an uneasiness that through some unwitting slip all hell may break loose.

Yet, after Rousseau had given the social contract a new twist with his notion of the General Will, the same philosophy, it may be said, became the idea source of the French Revolution also.

Father Murray goes back to the Declaration of Independence, too, though I may add, with considerably more historical perception.

Here there may be an analogy with cancer: we can detect cancers by their rapidly accelerating growth, determinable only when related to the more normal rate of healthy growth.

Any abilities I may have were achieved in their present shape from experience in sharing in the growth and control of my business, coupled with raising my family.

That, however, may also bring the police, if the thinking does not meet with social approval.

Like Roosevelt, he can distinguish an attitude toward a Russian leader he may share with a host of Americans from the responsibilities diplomatic convention may impose upon him.

All we want from Dr. Huxley's statement is the feeling that this is an open world, in the view of the best scientific opinion, with practically no directional commitments as to what may happen next, and no important confinements with respect to what may be possible.

It must be granted that the flouting of convention, no matter how well intentioned one may be, is sure to lead to trouble, or at least to the discomfort that goes with social disapproval.

Moreover, because of the particular blot on your family escutcheon through what may only have been one unbridled moment on your grandmother's part, and because you had the lean-to kitchen and trundle bed of your childhood to outgrow, what you obviously most desired with both your conscious and unconscious person, what you bent your whole will, sensibility, and intelligence upon, was to be a lady.

The United States is always ready to participate with the Soviet Union in serious discussion of these or any other subjects that may lead to peace with justice.

He may be the only song writer ever to have collaborated with a secretary of the U. S. Treasury ; ;