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One and downside
One downside, however, is that complexes may not separate cleanly or predictably, since they cannot move through the polyacrylamide gel as quickly as individual, denatured proteins.
One downside of ready-made eyeglasses is that their prescription is the same for each eye.
One downside caused by the increased strength of steel in the neck of these cases ( compared to the annealed neck of a brass case ) is that propellant gas can blow back past the neck and into the chamber.
One downside of this approach is that exchange rate appreciation would reduce the competitiveness of the export sector.
One downside of this type of mod is that leaked content can be revealed.
One downside of the building of the new line ( and resulting closure of the old ) was that Oodnadatta and other communities along the route of the original line lost their railway service.
One downside to the season was Arsenal's failure to progress to the quarter-finals of the European Cup.
One serious downside to these higher wing loadings is at low speed, when there simply isn't enough wing left to provide lift to keep the plane flying.
One downside to this type of incremental compiler is that it cannot easily optimize the code that it compiles, due to locality and the limited scope of what is changed.
One downside is there was no option of a five-speed transmission.
One downside of this technique is that the rocket blast usually injures the player ; this can be coupled with further damage if the player falls large distances to the ground.
One downside of the weapon mounted light is that it is always aimed parallel to the bore, so illuminating an object means that it is also targeted.
One downside to thermoelectric energy conversion is low efficiency ( currently less than 10 %).
One downside to 2. 4 GHz is that precautions must be taken during installation since certain materials such as carbon fiber can mask the signal.
One downside to this method was that since the film was exposed twice, there was always the risk of accidentally overexposing the film and ruining the footage filmed earlier.
One downside, only realized later, is that the current draw of the flip-flop was not balanced, so storing different numbers in them could lead to dramatically different current needs on the power supply — something that should be avoided wherever possible to reduce noise generated when the power draw increases or decreases.

One and was
One thing was certain -- his method was effective, so effective that after a time even the warning notices were often unnecessary.
One of Greg's bombs hung up, and he was miles from the target before he could get rid of it.
One swallow was all he would have ; ;
One girl expressed what was obviously in their minds.
One is tempted to say that, on the difference between the concepts of sovereignty in these two preambles, the worst war of the Nineteenth century was fought.
One beatnik got the woman he was living with so involved in drugs and self-analysis and all-night sessions of sex that she was beginning to crack up.
One evening, while a volley-ball game was being played in the yard among the prisoners remaining there, a simulated melee was staged -- just as the gates were opened to admit other prisoners returning from work.
One of the pictures was of a man with hat drawn over his face ceremoniously lighting a cigarette ; ;
One thing Papa had not taught Henrietta was how to handle a young man as high-spirited and opinionated as herself.
One cause of Schopenhauer's pessimism was the fact that he failed to learn the guitar.
One was an article on the U.N. by Alice Widener from the Cincinnati Enquirer.
One day he assigned me to lay bare a `` plot '' by the Duponts to supply munitions to a wholly fictitious revolution he said was about to occur in Cuba.
One shawl was so tremendous that she could not wear it, so she draped it over the banister on the second floor, and it hung over the stairway.
One White House dog was immortalized in a painting.
One person she helped was my brother.
One of Sherman's most serious shortcomings, however, was his mistrust of his cavalry.
One can imagine that with her and Gorton there it was no place for anyone with weak nerves.
One historical authority presents laborious and circuitous testimony tending to arouse suspicion that Massachusetts was behind the clouds settling down on the embattled Gorton.
One of the people who was afraid of Alfred was his own brother, Lew.
One example of this was his assertion that `` all servile revolts must be dealt with by physical force ''.
One day he was visited by a delegation of would-be imitators who wanted to know his secret.

One and new
One Monday morning I saw him approach the store with a woman and introduce me to her as my new Aunt.
One reason is, of course, that the new scepticism has been willing to maintain the general picture of the invasions as portrayed in the traditional sources.
One is impressed with the dignity, clarity and beauty of this new translation into contemporary English, and there is no doubt that the meaning of the Bible is more easily understandable to the general reader in contemporary language in the frequently archaic words and phrases of the King James.
One of the inescapable realities of the Cold War is that it has thrust upon the West a wholly new and historically unique set of moral dilemmas.
One of the reporters called to him: `` Anything new, Lieutenant ''??
One afternoon, as the women sat clucking softly, a new carload of people pulled up at the gate.
One indication of the merits of the new management is found in the fact that during the period 1951-1956, while total annual mileage put on the vehicles increased 35%, the total maintenance cost increased only 11%.
One way that this can be done, other than by hiring new high-priced professors, is by constantly encouraging the department members to raise their standards of performance.
The exercise I shall discuss in this -- the first of a new series of articles on muscle definition-specialization of a particular body part -- is the One Leg Lunge.
One of the more remarkable of the new cooling systems is one that can be switched to heating.
One could assume the new term was coined and adopted by Athenian democrats.
Plans were also made for a new retractable-roof ballpark, Bank One Ballpark, nicknamed the BOB, ( renamed in 2005 to Chase Field ) to be built in an industrial / warehouse district on the southeast edge of downtown Phoenix, one block from the Suns ' America West Arena ( now US Airways Center ).
One of the things the court has to do is figure out how to answer new questions, and that is what happened in this case.
One characteristic of American cooking is the fusion of multiple ethnic or regional approaches into completely new cooking styles.
They rented the apartment of an American man who was away for the summer, and Nin came across a number of French paperbacks: " One by one, I read these books, which were completely new to me.
One condition placed on the Bauhaus in this new political environment was the exhibition of work undertaken at the school.
One was Fred Hoyle's steady state model, whereby new matter would be created as the Universe seemed to expand.
Bulletins on BBC One moved into a new set in January 2003 although retained the previous ivory Lambie-Nairn titles until February 2004.
The latter two are mostly reserved for students in the new Vic One Programme.
Motor Racing Developments initially concentrated on making money by building cars for sale to customers in lower formulae, so the new car for the Formula One team was not ready until partway through the 1962 Formula One season.
One of the goals of these efforts is to measure the basic parameters of the Lambda-CDM model with increasing accuracy, as well as to test the predictions of the Big Bang model and look for new physics.
One of the new ownership group's first acts was to assure Cleveland fans they would give Brown the same kind of leeway.
The pair had unexpected success in their first season finishing just outside the play-offs, and 1992 – 93 began promisingly and Charlton looked good bets for promotion in the new Division One ( the new name of the old Second Division following the formation of the Premier League ).

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